The global financial crisis has created a structural break in the global economy. Businesses thus need to reassess the strategies they have developed to operate in a highly integrated global economy. Initial reactions have often been defensive as companies downsize and call for government support. However, times of crisis are also times of opportunity. In the short-term, opportunities arise for instance in 'value for money' segments. However, for long term opportunities, businesses have to develop foresight to use the economic downturn to position themselves for the next upswing.The current public debate largely focuses on the origins of the crisis, yet it is time look forward to address the question, how can businesses survive the crisis, and position themselves for the recovery whenever it may come? This paper aims to initiate this forwardlooking debate. The main focus thus is on generating ideas on how to move forward, rather than to provide definitive answers.Analyzing the financial downturn from a strategic management perspective, this paper first aims to synthesize the main shifts in key markets, and the implications of increased volatility and government interventions. On this basis, ideas for promising strategies are suggested, distinguishing critically between survival strategies for the crisis, and strategic positioning for the next upswing. Business leaders need to develop scenarios of the new economy, and envisage their role in it.