Glomangiopericytoma (Hemangiopericytoma) of the maxillary sinus and sinonasal tract

Saad, Samaher Al; Hadlaq, Razan Al; Al-Zaher, Nabil

doi:10.1016/j.hemonc.2016.12.001

Cited by 11 publications

(14 citation statements)

References 11 publications

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“…(4) With less than 200 cases of sinonasal hemangiopericytomas reported in the litera-ture, only limited assumptions can be made about the tumor. (10,11) This is another case of sinonasal hemangiopericytoma to add to the small but growing body of literature on this disease. Historically, open surgical methods for tumor extirpation have been considered as standard treatment, although endoscopic resection has increased in recent decades.…”

Section: Discussionmentioning

confidence: 98%

Endoscopic management of sinonasal hemangiopericytoma: case report and literature review

et al. 2018

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Section: Discussionmentioning

confidence: 98%

Endoscopic management of sinonasal hemangiopericytoma: case report and literature review

et al. 2018

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“…In our case, the patient was in his 60s, hypertensive, and interestingly, underwent septoplasty 6 years previously; yet the etiology of the patient's tumor is unknown. Moreover, there are few reported cases and only one in this region [ 9 ]. This could be attributed to the GPC being missed or underdiagnosed, since the tumors are indolent and harbor features similar to those found in sinonasal polyps, for which it might be mistaken [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

A rare case of glomangiopericytoma in the nasal cavity: A case report in light of recent literature

Almarri

Alnatheer

Abuhaimed

et al. 2022

Annals of Medicine &Amp; Surgery

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“…Surgical resection by ESS was performed in 13 (57%) of the 23 patients. Based on tumor extension, partial resection of the maxilla [9] or external incisional surgery has been reported [4–6]. We performed ESS with 5-mm safety margins for the basal part of the tumor.…”

Section: Discussionmentioning

confidence: 99%

Glomangiopericytoma of the Nasal Cavity with CTNNB1 p.S37C Mutation: A Case Report and Literature Review

Kono

Bandoh

Matsuoka

et al. 2018

Head and Neck Pathol

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Glomangiopericytoma (GPC) is a rare mesenchymal tumor arising from the nasal cavity or paranasal sinuses. GPC was categorized as a borderline and low-malignant-potential tumor by the World Health Organization in 2005 and accounts for less than 0.5% of all sinonasal tumors. We report a case of GPC in a 74-year-old woman with a history of recurrent epistaxis and nasal obstruction. A reddish tumor was seen in the right nasal cavity. Enhanced computed tomography showed a mass lesion occupying the right nasal cavity. The tumor, which originated from the nasal septum in the olfactory fissure area, was resected with 5-mm mucosal margins by endoscopic sinus surgery. Histologic examination revealed a uniform proliferation of oval-to-short spindle-shaped cells beneath the epithelium. Immunohistologic analysis demonstrated the tumor cells were positive for α-smooth muscle actin, β-catenin and Vimentin, and negative for AE1/AE3, Bcl-2, CD34, CD117, Factor VIIIR Ag, S-100 protein, or STAT6. The percentage of Ki-67-positive cells was approximately 5%. Genetic analysis using next-generation sequencing revealed a missense mutation in the CTNNB1 gene (c.110C > G, p.S37C). While other CTNNB1 mutations have been described in GPC; this is the first report of this specific mutation. The mutation was confirmed using Sanger sequencing.

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Glomangiopericytoma (Hemangiopericytoma) of the maxillary sinus and sinonasal tract

Cited by 11 publications

References 11 publications

Endoscopic management of sinonasal hemangiopericytoma: case report and literature review

Endoscopic management of sinonasal hemangiopericytoma: case report and literature review

A rare case of glomangiopericytoma in the nasal cavity: A case report in light of recent literature

Glomangiopericytoma of the Nasal Cavity with CTNNB1 p.S37C Mutation: A Case Report and Literature Review

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