Glomerular Pathology in Patients with HIV Infection

Morales, Enrique; Gutiérrez‐Solís, Elena; Gutiérrez, Eduardo; Praga, Manuel

doi:10.5772/22832

Cited by 1 publication

(2 citation statements)

References 62 publications

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“…However, several researchers [19]- [22] reported that plasma apheresis in combination with appropriate drug prescription have been in use and appear to have favorable results. Our CA model is thus expected to provide valuable augmentation to current understanding of the impact of such treatment where experimental data may not be readily available.…”

Section:  mentioning

confidence: 99%

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Investigating Combined Drug and Plasma Apheresis Therapy of HIV Infection by Double Compartment Cellular Automata Simulation

Moonchai¹,

Lenbury²

2016

IJCTE

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Abstract-It has become widely acknowledged that potent combination drug therapy of patients infected with Human Immunodeficiency Virus can significantly prolong life, but exerts detrimental effect on a patient's quality of life. Lymph nodes and lymphatic tissue are busy sites of immunological activity. Germs are brought there by the cells of the immune system to be broken down and analyzed. However, clinics commonly used blood tests for viral load therein to assess the effect of drug therapy. We are therefore of the opinion that most cellular automata models in the past that only considered viral proliferation in the lymph node cannot give a sufficiently accurate picture of the dynamics of HIV infection, especially when the impact of treatments that combine both drugs and plasma apheresis are in question. We thus present a two-compartment cellular automata (CA) model, which simulates the dynamics of HIV infection in both the lymph node and blood compartments when drugs and plasma apheresis are applied simultaneously. It is found that the combined usage of these two types of therapy yields more favorable outcome than the sole use of plasma apheresis.

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Section:  mentioning

confidence: 99%

“…Several research reports have indicated that plasma apheresis may offer a good alternative for the treatment of AIDS patients [16]- [19]. Several researchers [19]- [22] have reported that plasma apheresis in combination with drug prescription can be efficacious treatment of HIV patients.…”

Section: Introductionmentioning

confidence: 99%

Investigating Combined Drug and Plasma Apheresis Therapy of HIV Infection by Double Compartment Cellular Automata Simulation

Moonchai¹,

Lenbury²

2016

IJCTE

View full text Add to dashboard Cite

show abstract

Glomerular Pathology in Patients with HIV Infection

Cited by 1 publication

References 62 publications

Investigating Combined Drug and Plasma Apheresis Therapy of HIV Infection by Double Compartment Cellular Automata Simulation

Investigating Combined Drug and Plasma Apheresis Therapy of HIV Infection by Double Compartment Cellular Automata Simulation

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