Glomerulonephritis in Older Age Groups

Nesson, H. Richard; Robbins, Stanley L.

doi:10.1001/archinte.1960.00270130039005

Cited by 35 publications

(11 citation statements)

References 22 publications

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“…However, for reasons which are not entirely clear, the coexistence of these two eniities has been rarely noted [2][3][4][5]. Some patients with diabetes mellitus have been described in large series of cases with acute poststreptococ cal glomerulonephritis [5][6][7][8][9][10].…”

Section: Discussionmentioning

confidence: 99%

“…Diabetes mellitus is a disease affecting approximately 1-2% of the United States population [1], Major renal problems usually associated with diabetic patients are urinary tract infection, acute papillary necrosis and diabetic nephropathy [1], The occurrence of immune complex mediated glomerulonephritis (ICGN) in patients with diabetic nephropathy has been noted infrequently [2][3][4][5] as has been the presence of diabetic nephropathy in series of patients with ICGN [6][7][8][9][10]. Furthermore, details of the clinical course and renal morphology in patients with these two diseases are limited.…”

Section: Introductionmentioning

confidence: 99%

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Diabetes Mellitus with Immune Complex Glomerulonephritis

Aziz

Cohen

Winer

et al. 1979

Nephron

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The present study describes 3 patients with the simultaneous occurrence of diabetic nephropathy and immune-complex mediated glomerulonephritis. Renal manifestation included proteinuria and hematuria which were preceded by or co-existent with an infectious process. Renal histology showed the characteristic change of diabetic nephropathy along with those of immune complex glomerulonephritis. Immunofluorescence studies showed a linear pattern with a superimposed granular pattern of IgG and C₃ deposits. Renal function and urinary findings improved in the 2 patients who were followed up.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Diabetes Mellitus with Immune Complex Glomerulonephritis

Aziz

Cohen

Winer

et al. 1979

Nephron

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“…The finding of unsuspected glomerulonephritis at necropsy in the elderly is not uncommon, since dyspnoea and oedema in this age group is presumed to be due to myocardial disease [5,6], A thorough investigation in cluding renal biopsy is as necessary in making a diagnosis in the elderly as in younger patients. If this is done the response to treatment is good, as seen in our patients and as reported earlier [7].…”

Section: Discussionmentioning

confidence: 99%

Medical Renal Disease in the Elderly in a Southern Indian Hospital

Hariharan

Date

Kirubakaran

et al. 1988

Nephron

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A review of 85 patients aged 60 years or more, treated in a southern Indian hospital for conditions requiring renal biopsy, showed that diffuse poliferative glomerulonephritis was the most frequent diagnosis, being present in 24 cases of whom 11 had elevated serum streptococcal antibody titres. Infections were also important in 2 patients with amyloidosis secondary to tuberculosis, in 3 patients with acute tubular necrosis following infectious gastroenteritis and in a patient with acute pyaemic interstitial nephritis with septicaemia. Drugs including indigenous medicines were the other important cause of renal disease, being implicated in 11 cases.

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“…The correct diagnosis was established in only 1 of those 7 patients premortem and this was felt to contribute to the high mortality rate. Nesson and Rob bins [35] found that nearly half of the patients with a postmortem diagnosis of acute glomerulonephritis were over the age of 50 at autopsy. All 7 of the patients reported by Lee et al [5] died; however, these patients had been referred to a hemodialysis unit, so are probably not representative of the general population.…”

Section: Discussionmentioning

confidence: 99%

Poststreptococcal Glomerulonephritis in the Elderly

Melby¹,

Musick²,

Luger³

et al. 1987

Am J Nephrol

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Acute poststreptococcal glomerulonephritis (PSGN) is uncommonly seen in the elderly population and its diagnosis is not without some difficulty because clinical manifestations may mimic other diseases. Renal biopsy for diagnosis and early intervention, if indicated, is very valuable in such a situation. We present here a case of an elderly patient with PSGN and a review of the literature. In addition to the typical clinical manifestations of the disease, dyspnea and pulmonary congestion are commonly present in elderly patients, probably a result of excessive salt and water retention in the face of compromised cardiovascular function. Elderly patients with PSGN appear to have a remarkably poor prognosis, with significant incidences of acute mortality and chronic renal disease. Our patient had the unusual finding of a large number of glomerular crescents with near complete clinical recovery after short-term follow-up.

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Glomerulonephritis in Older Age Groups

Cited by 35 publications

References 22 publications

Diabetes Mellitus with Immune Complex Glomerulonephritis

Diabetes Mellitus with Immune Complex Glomerulonephritis

Medical Renal Disease in the Elderly in a Southern Indian Hospital

Poststreptococcal Glomerulonephritis in the Elderly

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