Glomus tumor: A rare location in the upper lip

Rallis, George; Komis, Constantine; Mahera, H

doi:10.1016/j.tripleo.2004.02.005

Cited by 18 publications

(6 citation statements)

References 30 publications

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“…The immunohistochemical profile of glomus tumor cells includes positivity for vimentin, smooth muscle actin, and muscle-specific actin; moreover, positivity for desmin, CD34, and BRAF mutations has been identified in some cases [ 44 ]. Conversely, these tumors yield negative results for S-100, myoglobin, neurofilaments, and factor VIII-related antigen [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

Glomus tumor in the floor of the mouth: a case report and review of the literature

Zou

Jia

et al. 2018

World J Surg Onc

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BackgroundGlomus tumors are rare benign neoplasms that usually occur in the upper and lower extremities. Oral cavity involvement is exceptionally rare, with only a few cases reported to date.Case presentationA 24-year-old woman with complaints of swelling in the left floor of her mouth for 6 months was referred to our institution. Her swallowing function was slightly affected; however, she did not have pain or tongue paralysis. Enhanced computed tomography revealed a 2.8 × 1.8 × 2.1 cm-sized well-defined, solid, heterogeneous nodule above the mylohyoid muscle. The mandible appeared to be uninvolved. The patient underwent surgery via an intraoral approach; histopathological examination revealed a glomus tumor. The patient has had no evidence of recurrence over 4 years of follow-up.ConclusionsGlomus tumors should be considered when patients present with painless nodules in the floor of the mouth.

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Section: Discussionmentioning

confidence: 99%

Glomus tumor in the floor of the mouth: a case report and review of the literature

Zou

Jia

et al. 2018

World J Surg Onc

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“…Among perivascular myoid tumors, ALM and SMF are relatively common in the oral region (11, 12), but oral presentation of GT is very rare, with fewer than 20 cases in the English literature (13). Approximately 10 years have elapsed since the original series appeared (6, 7), yet the number of published accounts of intra‐oral MPC was only 3 (10, 14, 15).…”

Section: Introductionmentioning

confidence: 99%

Perivascular myoid tumors of the oral region: a clinicopathologic re‐evaluation of 35 cases

Ide

Mishima

Yamada

et al. 2007

J Oral Pathology Medicine

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“…Our case is rare of reported cases of glomus tumor localized at the mandible in the English-language literature and the case involving the mandible and teeth [7–10]. Previous reports suggest a male predilection for glomus tumors in the oral cavity.…”

Section: Discussionmentioning

confidence: 61%

“…The glomus cell resembles a modified smooth muscle cell of the normal glomus body in the subcutaneous tissue, where it serves as a specialized form of arteriovenous anastomosis for the control of blood pressure and temperature [6, 7]. The vast majority of glomus tumors occur in the distal extremities, particularly the subungual region, hand, wrist, and foot, but rare cases have been reported in almost every location of the body [4].…”

Section: Discussionmentioning

confidence: 99%

The glomus tumor resorbed bone and teeth in the mandible: a case report

et al. 2018

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BackgroundA glomus tumor is a rare neoplasm usually found in the dermis or subcutaneous tissue of the extremities. It is rare for the glomus tumor to occur on the head and face. Only 26 glomus tumors of the oral region and affected bone have been reported in the English-language literature (Table 1). We report a case of a glomus tumor at the mandible. As a new point, the glomus tumor resorbed a bone and teeth roots when the tumor progressed into the mandible.Case presentationThe patient was a 44-year-old Japanese man who complained swelling of the right mandible. Radiographic examination showed a multilocular radiolucency area in the left mandible. Radiographic findings on our case resembled those of a common benign tumor. The lesion occupied to the premolar and molar area and revealed that the tumor resorbed the roots of the teeth. The lesion was removed surgically with the buccal cortical bone and buccal mucosa in contact with the mass of the tumor. The mass fully excised intraorally under general anesthesia, and the inferior alveolar nerve in contact with the mass was preserved.The specimen was pathologically diagnosed as a glomus tumor. Immunohistochemical staining was positive for vimentin, muscle-specific actin/HHF35, and calponin. A hairline-shaped area of positive staining for type IV collagen surrounding the tumor cells was also observed. In contrast, staining for alpha-SMA, cytokeratin (AE1/AE3), cytokeratin (CAM5.2), CK19, CD31, CD34, CD68, p63, S-100, Factor VIII, and desmin was all negative. The Ki-67 labeling index was almost 1%.A recurrent tumor was again detected in the site below the primary tumor at an 8-year follow-up, and it was surgically removed. The patient has had no symptoms of recurrence in 2 years after the second operation.ConclusionThe glomus tumor resorbed a bone and teeth roots when the tumor progressed into the mandible. The immunohistochemical features of the tumor were consistent with those described in previous reports. It is important to completely remove the Glomus tumor.

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Glomus tumor: A rare location in the upper lip

Cited by 18 publications

References 30 publications

Glomus tumor in the floor of the mouth: a case report and review of the literature

Glomus tumor in the floor of the mouth: a case report and review of the literature

Perivascular myoid tumors of the oral region: a clinicopathologic re‐evaluation of 35 cases

The glomus tumor resorbed bone and teeth in the mandible: a case report

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