Glomus tumor in the stomach: A case report and review of the literature

Chen, Kaibo; Chen, Li

doi:10.3892/ol.2014.1986

Cited by 22 publications

(28 citation statements)

References 23 publications

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“…They are often initially misdiagnosed as the more common GIST, only to be definitively diagnosed by immunohistochemistry on final pathologic specimen. Patients are typically symptomatic at time of presentation, with gastrointestinal bleeding and epigastric discomfort being common [9]. Although endoscopic fine needle aspiration has been described for successful preoperative diagnosis [10], this is usually of low yield given the intramural nature of the tumor.…”

Section: Discussionmentioning

confidence: 99%

Gastric Glomus Tumor: An Uncommon Source for an Acute Upper GI Bleed

Morte

Bingham

Sohn

2018

Case Reports in Gastrointestinal Medicine

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Background Glomus tumors are uncommon mesenchymal neoplasms originating from modified smooth muscle cells in the glomus body. They are generally small, solitary lesions found in the distal extremities. Rarely, involvement in the abdominal viscera can occur. In such cases, hematemesis/melena and epigastric discomfort are the most common initial symptoms. Although gastric glomus tumors can demonstrate malignant behavior, criteria for identifying malignant potential have yet to be established. Case Presentation We present a rare case of gastric glomus tumor in an otherwise healthy 41-year-old female. The patient initially presented with a significant upper GI bleed requiring a 4 U PRBC transfusion for stabilization. An upper endoscopy with endoscopic ultrasound identified an ulcerated, submucosal mass thought to be consistent with GI stromal tumor (GIST). Once clinically stable, she was scheduled for elective resection. However, prior to resection she experienced a second hemodynamically significant upper GI bleed and underwent emergent laparotomy with distal gastrectomy. Pathologic examination revealed a 3 cm glomus tumor. Conclusion Gastric glomus tumors are rare solitary submucosal tumors for which preoperative diagnosis is challenging and can be confused with a GIST. Local resection with negative margins is the preferred treatment and the exact diagnosis relies heavily on histopathological examinations. Currently, there are no clear guidelines regarding the staging and malignant potential of glomus tumors of the stomach.

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Section: Discussionmentioning

confidence: 99%

Gastric Glomus Tumor: An Uncommon Source for an Acute Upper GI Bleed

Morte

Bingham

Sohn

2018

Case Reports in Gastrointestinal Medicine

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“…Other mesenchymal tumours, such as neuroendocrine tumours, haemangiomas and GIST's, may present similarly on CT scans. Endoscopic or FNA biopsies may distinguish glomus tumours from other gastric tumours, but may be misleading or might not contribute to the preoperative diagnosis 2 5 6. In these situations, a complete resection of the tumour is recommended.…”

Section: Discussionmentioning

confidence: 99%

“…Within the gastrointestinal tract, they occur most often in the stomach. Typically, they are described as solitary, well-defined gastric submucosal tumours in the antrum, with non-specific clinical manifestations 2. Most patients are asymptomatic, but may report of ulcer-like symptoms or even suffer from gastrointestinal bleeding 2 3.…”

Section: Introductionmentioning

confidence: 99%

“…Typically, they are described as solitary, well-defined gastric submucosal tumours in the antrum, with non-specific clinical manifestations 2. Most patients are asymptomatic, but may report of ulcer-like symptoms or even suffer from gastrointestinal bleeding 2 3. Gastrointestinal stromal tumours (GISTs) are important in the differential diagnosis and are the most common malignant stromal tumours of the stomach.…”

Section: Introductionmentioning

confidence: 99%

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Glomus tumour of the stomach

2016

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Glomus tumours are benign tumours typically arising from the glomus bodies and primarily found under the fingernails or toenails. These rare neoplasms account for <2% of all soft tissue tumours and are generally not found in the gastrointestinal tract. We report a case of a 40-year-old man presenting with recurrent epigastric pain and pyrosis. Endoscopy revealed a solitary tumour in the antrum of the stomach. Fine-needle aspiration biopsy was suspicious for a gastrointestinal stroma tumour. After CT indicated the resectability of the tumour, showing neither lymphatic nor distant metastases, a laparoscopic-assisted gastric wedge resection was performed. Surprisingly, histology revealed a glomus tumour of the stomach.

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“…The former has an advantage in identifying the layer of tumour origin, and the latter is advantageous in tumour characterization with the use of contrast enhancement [6] . EUS will show a hypoechoic, well-circumscribed mass located in the third and/or fourth EUS layer [7,8,9,10] EUS-guided biopsy is now a well established modality for sampling submucosal lesions [9,11] .…”

Section: Discussionmentioning

confidence: 99%