Glucosamine Acetoacetate Condensate Iii. Its Effect Upon Serum Insulin and Glucose Uptake by Muscle and Liver

Abstract

SUMMARY : The effect of glucosamine-acetoacetate condensate (pyrrolecondensate) upon insulin and glucose plasma levels of white albino rats was determined.Parallel experiments were made upon the rate of incorporation of uniformly labeled glucose-C-14 into liver and muscle tissue.Our results show that pyrrole-condensate is capable of significantly increasing the levels of insulin and reducing the levels of glucose, in the serum of white albino rats. The incorporation of glucose into liver and muscle was substantially increased in the pyrrole-treated rat as compared with the normal.