Glucose Concentrations for Routine Intravenous Infusion in Pediatric Outpatient Surgery

Płynoterapia śródoperacyjna w praktyce pediatrycznej — porównanie wybranych płynów infuzyjnych

“…The above findings are in accordance with the studies carried out in the last two decades by other authors, who estimated the risk of hypoglycaemia at 0−1% [22]. At present, this problem can be considered marginal due to shortened preoperative fasting-unlimited clear fluids are allowed up to 2 hours before anaesthesia [5].…”

Perioperative blood glucose in a paediatric daycase facility: Effects of fasting and maintenance fluid

“…[2][3][4] Although several clinicians have reported maintenance of normoglycaemia preoperatively, and hyperglycaemic response to surgery and anaesthesia in healthy children in spite of fasting; [5][6][7][8][9][10][11][12][13][14] others have observed hypoglycaemia in a significant minority. [3,[15][16][17][18][19][20][21][22][23] Failure to demonstrate hyperglycaemia or outright hypoglycaemic response to anaesthesia and surgery has been reported by a few. [19,24] A high incidence of preoperative hypoglycaemia was observed among low percentile weight children (40%) by Ilori et al [3] Hypoglycaemia could be a cause of significant morbidity and mortality in the perioperative periods.…”

“…These include 5%, 2.5%, 2%, and 1%. [14][15][16][17][18][19][20][21][22][23][24] However, these are not commercially available in many centres in the sub-Sahara and the pharmacy departments may not be adequately equipped to handle production of these fluids. Currently 4.3% dextrose in 0.18% saline (DS) is the fluid being used in many centres in Nigeria for paediatric perioperative fluid management.…”

Optimal dose and duration of glucose administration during fasting period preceding surgery in rabbits

“…There has been considerable controversy regarding glucose administration during the intraoperative period, since glucose easily exacerbates carbon dioxide production and intracellular lactic acidosis caused by surgical stress [1]. However, in many circumstances, intraoperative glucose administration may be advantageous to inhibit catabolism and improve fat and carbohydrate metabolism [2][3][4]. Our previous animal study also showed that intraoperative glucose supplementation is effective in preventing hepatic glycogen depletion, and indicated further that the optimal dose to avoid glucose overloading was 0.1-0.2 g·kg Ϫ1 ·h Ϫ1 [5].…”