Glucose microenvironment sensitive degradation of arginine modified calcium sulfate reinforced poly(lactide-<i>co</i>-glycolide) composite scaffolds

Zhu, Yongzhan; Li, Yinghao; Zhou, Xiaosong; Li, Haoxuan; Guo, Min; Zhang, Peibiao

doi:10.1039/d3tb01595e

J. Mater. Chem. B

2024

DOI: 10.1039/d3tb01595e

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Glucose microenvironment sensitive degradation of arginine modified calcium sulfate reinforced poly(lactide-co-glycolide) composite scaffolds

Yongzhan Zhu,

Yinghao Li,

Xiaosong Zhou

et al.

Abstract: Poly(lactide-co-glycolide) (PLGA) and calcium sulfate composites are promising biodegradable biomaterials but are still challenging to use in people with high levels of blood glucose or diabetes.

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Recent Advances in Whiskers: Properties and Clinical Applications in Dentistry

Han,

Zhang,

Liu

et al. 2024

IJN

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Whiskers are nanoscale, high-strength fibrous crystals with a wide range of potential applications in dentistry owing to their unique mechanical, thermal, electrical, and biological properties. They possess high strength, a high modulus of elasticity and good biocompatibility. Hence, adding these crystals to dental composites as reinforcement can considerably improve the mechanical properties and durability of restorations. Additionally, whiskers are involved in inducing the value-added differentiation of osteoblasts, odontogenic osteocytes, and pulp stem cells, and promoting the regeneration of alveolar bone, periodontal tissue, and pulp tissue. They can also enhance the mucosal barrier function, inhibit the proliferation of tumor cells, control inflammation, and aid in cancer prevention. This review comprehensively summarizes the classification, properties, growth mechanisms and preparation methods of whiskers and focuses on their application in dentistry. Due to their unique physicochemical properties, excellent biological properties, and nanoscale characteristics, whiskers show great potential for application in bone, periodontal, and pulp tissue regeneration. Additionally, they can be used to prevent and treat oral cancer and improve medical devices, thus making them a promising new material in dentistry.

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Recent Advances in Whiskers: Properties and Clinical Applications in Dentistry

Han,

Zhang,

Liu

et al. 2024

IJN

View full text Add to dashboard Cite

show abstract

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Glucose microenvironment sensitive degradation of arginine modified calcium sulfate reinforced poly(lactide-co-glycolide) composite scaffolds

Abstract: Poly(lactide-co-glycolide) (PLGA) and calcium sulfate composites are promising biodegradable biomaterials but are still challenging to use in people with high levels of blood glucose or diabetes.

Cited by 1 publication

References 42 publications

Recent Advances in Whiskers: Properties and Clinical Applications in Dentistry

Recent Advances in Whiskers: Properties and Clinical Applications in Dentistry

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