Glucosyl terpenates from the dried fruits of Prunus domestica L.

Kayano, Shin-ichi; Kikuzaki, Hiroe; Hashimoto, S.; Kasamatsu, Kumi; Ikami, Takao; Nakatani, Nobuji

doi:10.1016/j.phytol.2014.03.006

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…A literature search led to the structure of three isomeric metabolites, among which 3-O-p-coumaroylsucrose was assigned as the structure. This metabolite was previously identified in dried fruits of Prunus domestica [21].…”

Section: Chemistrymentioning

confidence: 81%

NOx-, IL-1β-, TNF-α-, and IL-6-Inhibiting Effects and Trypanocidal Activity of Banana (Musa acuminata) Bracts and Flowers: UPLC-HRESI-MS Detection of Phenylpropanoid Sucrose Esters

et al. 2019

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Banana inflorescences are a byproduct of banana cultivation consumed in various regions of Brazil as a non-conventional food. This byproduct represents an alternative food supply that can contribute to the resolution of nutritional problems and hunger. This product is also used in Asia as a traditional remedy for the treatment of various illnesses such as bronchitis and dysentery. However, there is a lack of chemical and pharmacological data to support its consumption as a functional food. Therefore, this work aimed to study the anti-inflammatory action of Musa acuminata blossom by quantifying the cytokine levels (NO x , IL-1β, TNF-α, and IL-6) in peritoneal neutrophils, and to study its antiparasitic activities using the intracellular forms of T. cruzi, L. amazonensis, and L. infantum. This work also aimed to establish the chemical profile of the inflorescence using UPLC-ESI-MS analysis. Flowers and the crude bract extracts were partitioned in dichloromethane and n-butanol to afford four fractions (FDCM, FNBU, BDCM, and BNBU). FDCM showed moderate trypanocidal activity and promising anti-inflammatory properties by inhibiting IL-1β, TNF-α, and IL-6. BDCM significantly inhibited the secretion of TNF-α, while BNBU was active against IL-6 and NO x . LCMS data of these fractions revealed an unprecedented presence of arylpropanoid sucroses alongside flavonoids, triterpenes, benzofurans, stilbenes, and iridoids. The obtained results revealed that banana inflorescences could be used as an anti-inflammatory food ingredient to control inflammatory diseases.

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Section: Chemistrymentioning

confidence: 81%

NOx-, IL-1β-, TNF-α-, and IL-6-Inhibiting Effects and Trypanocidal Activity of Banana (Musa acuminata) Bracts and Flowers: UPLC-HRESI-MS Detection of Phenylpropanoid Sucrose Esters

et al. 2019

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“…The LC-HRMS profiles of the PC, PD, and PF extracts highlighted the occurrence of several metabolites in P. cerasifera, the structures of which could be assigned by a comparison between the molecular formulae, fragmentation patterns, and retention times and the literature data and metabolite databases, allowing us to putatively identify hydroxycinnamic acid derivatives, flavonols, flavan-3-ols and proanthocyanidins, anthocyanins, organic acids, sugar alcohols (and their derivatives), glycosylated hydroxybenzaldehyde and benzylic alcohol derivatives, glycosyl terpenates, and glycosylated aliphatic alcohol derivatives (Table 4) [37,[49][50][51][52][53][54]. Except for compounds 28 and 67, which were previously described in the Rosaceae family [55,56] but not in the genus Prunus, and for compounds 35, 36, 43, and 54 described in families other than Rosaceae [57][58][59], to the best of our knowledge, most of these compounds have already been detected in plants belonging to the genus Prunus [60][61][62][63][64][65][66][67][68][69][70][71][72][73] but not in the species cerasifera. Only compounds 1, 2, 5, 7, 10, 12, 15, 18, 20, 29, 34, 42, 58, and 75 have already been described in this species [31,45,[74][75][76][77][78].…”

Section: Lc-hrms Analysismentioning

confidence: 83%

A New Bloody Pulp Selection of Myrobalan (Prunus cerasifera L.): Pomological Traits, Chemical Composition, and Nutraceutical Properties

Sottile

Napolitano

Badalamenti

et al. 2023

Foods

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A new accession of myrobalan (Prunus cerasifera L.) from Sicily (Italy) was studied for the first time for its chemical and nutraceutical properties. A description of the main morphological and pomological traits was created as a tool for characterization for consumers. For this purpose, three different extracts of fresh myrobalan fruits were subjected to different analyses, including the evaluation of total phenol (TPC), flavonoid (TFC), and anthocyanin (TAC) contents. The extracts exhibited a TPC in the range 34.52–97.63 mg gallic acid equivalent (GAE)/100 g fresh weight (FW), a TFC of 0.23–0.96 mg quercetin equivalent (QE)/100 g FW, and a TAC of 20.24–55.33 cyanidine-3-O-glucoside/100 g FW. LC-HRMS analysis evidenced that the compounds mainly belong to the flavonols, flavan-3-ols, proanthocyanidins, anthocyanins, hydroxycinnamic acid derivatives, and organic acids classes. A multitarget approach was used to assess the antioxidant properties by using FRAP, ABTS, DPPH, and β-carotene bleaching tests. Moreover, the myrobalan fruit extracts were tested as inhibitors of the key enzymes related to obesity and metabolic syndrome (α-glucosidase, α-amylase, and lipase). All extracts exhibited an ABTS radical scavenging activity that was higher than the positive control BHT (IC50 value in the range 1.19–2.97 μg/mL). Moreover, all extracts showed iron-reducing activity, with a potency similar to that of BHT (53.01–64.90 vs 3.26 μM Fe(II)/g). The PF extract exhibited a promising lipase inhibitory effect (IC50 value of 29.61 μg/mL).

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Chemical Constituents and Health Benefits of Four Chinese Plum Species

Liu

Nan

Nisar

et al. 2020

Journal of Food Quality

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Prunus is a large genus in the Rosaceae family of flowering plants, comprising over 340 species inhabiting variable landscapes in the world. Over 500 listed phytochemicals have been isolated from this single genus so far. The present study focused four Chinese Prunus species, viz., Prunus cerasifera, Prunus domestica, Prunus salicina, and Prunus spinosa, due to their uses, demand, nutritional value, medicinal importance, and diverse biological potential. The current review article highlights the details about the active phytochemicals and various pharmacological activities already reported. Almost 212 compounds, the majority of which are flavonoids, phenolic acids, anthocyanins, and their derivatives, which have been isolated from these four Prunus species fall in different categories and are helpful to evade chronic oxidative stress-mediated diseases. A huge variation exists in the total phytochemicals composition in different Prunus species, making these species to have different biological activities in multiple disease conditions, and even the same variety growing under different edaphic conditions may have different antioxidant capacities. It is suggested to perform extensive and indepth studies to find new phytochemicals from these four Chinese Prunus species which could boost the local industry to fulfill the increasing demands.

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Glucosyl terpenates from the dried fruits of Prunus domestica L.

Cited by 3 publications

References 22 publications

NOx-, IL-1β-, TNF-α-, and IL-6-Inhibiting Effects and Trypanocidal Activity of Banana (Musa acuminata) Bracts and Flowers: UPLC-HRESI-MS Detection of Phenylpropanoid Sucrose Esters

NOx-, IL-1β-, TNF-α-, and IL-6-Inhibiting Effects and Trypanocidal Activity of Banana (Musa acuminata) Bracts and Flowers: UPLC-HRESI-MS Detection of Phenylpropanoid Sucrose Esters

A New Bloody Pulp Selection of Myrobalan (Prunus cerasifera L.): Pomological Traits, Chemical Composition, and Nutraceutical Properties

Chemical Constituents and Health Benefits of Four Chinese Plum Species

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