We highlight the need for the development of comprehensive amplitude analysis methods to further our understanding of hadron spectroscopy. Reaction amplitudes constrained by first principles of S-matrix theory and by QCD phenomenology are needed to extract robust interpretations of the data from experiments and from lattice calculations.In the last two decades, high-energy physics experiments have delivered a lot of unexpected exotic hadron resonances, that challenge the minimal quark model lore of baryons with three quarks and mesons with a quark-antiquark pair. Candidates for tetraquarks, pentaquarks, molecules, and hadrons with gluonic degrees of freedom have been found [1,2]. Establishing the existence of isolated resonances that go beyond the minimal quark model is just the first step: one needs to identify the complete multiplets and study the differences and similarities among their members. This