Glukosemessung mit dem kontinuierlich messenden Glukosesensor CGMS® bei stoffwechselgesunden Schwangeren während Betamethasontherapie zur fetalen Lungenreifeinduktion

Schumacher, Anne; Sidor, J

doi:10.1055/s-2006-951743

Cited by 12 publications

(1 citation statement)

References 10 publications

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“…However, there are no guidelines for cases like this without diabetes mellitus. Star et al reported that prophylactic use of insulin was better [7], but Schumacher et al opposed this notion [8]. It is very difficult to extrapolate from these overseas reports why substantial tocolytic therapy in Japan is different from that in those other countries.…”

Section: Introductionmentioning

confidence: 99%

Ritodrine Should Be Carefully Administered during Antenatal Glucocorticoid Therapy Even in Nondiabetic Pregnancies

Ogawa

Matsuda

Kobayashi

et al. 2013

ISRN Obstetrics and Gynecology

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Aim. Antenatal glucocorticoid therapy (AGT) has been commonly used recently. However, this therapy has severe harmful effects such as maternal hyperglycemia. In Japan, ritodrine hydrochloride has been used as a tocolytic agent. In this study, we performed retrospective casecontrol study to clarify whether concomitant use of ritodrine and glucocorticoid was safe to pregnant women without diabetes mellitus. Methods. We reviewed the computerized records of pregnant women with pregestational diabetes (n = 9) and nondiabetes (n = 45) who gave birth at our hospital between 2002 and 2011. Cases and controls received AGT. Blood glucose after the therapy was analyzed, and additional volume of insulin was compared to that before the therapy. Results. From this study, 30 units of insulin were necessary when performing AGT in diabetic pregnant women. And also, an increase in blood glucose of 40 mg/dL was seen after the therapy even in nondiabetic pregnant women. Blood glucose increased significantly in the group that also received ritodrine, and it was shown that the number of pregnant women who might develop ketoacidosis might increase 11-fold. Conclusions. Ritodrine should be carefully administered during antenatal glucocorticoid therapy. It may be necessary to adequately monitor blood glucose, when performing the therapy, even in nondiabetic pregnant women.

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Section: Introductionmentioning

confidence: 99%