Glutarimides I. 3-alkyl-3-methylglutarimides

Chemistry of Guareschi Imides I

“…General procedure for preparation of Guareschi h i d e s (2).-The appropriate ketone (0.5 mole), 1.1 mole of freshly distilled ethyl cyanoacetate, and 225 ml. of alcoholic ammonia were mixed and refrigerated for 3 days in a well-stoppered flask.…”

“…a,a'-dicyano-&@dimethyl-N-methylglutarimide, and spUo-(3-aza-Payne (10). 2 Prepared according to directions given by Rapoport and 1,5-dicyano-2,4-dioxo-3-methyl-bicyclo-(3.1.l)-heptane-6,l '-cyclohexane).…”