Glutathione and the Pasteur reaction

Baker, Zelma

doi:10.1042/bj0310980

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Respiration and Glycolysis1

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1956

2004

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Cited by 11 publications

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“…In Table 1, oxygen uptake in the presence of thiols and tissue is reported without correction for the pressure changes in the absence of tissue. This is done because cerebral tissues are known to protect some thiols from oxidation (Baker, 1937). Also, a major interest in the present respiratory measurements lay in the change brought about by the addition of potassium chloride.…”

Section: Respiration and Glycolysismentioning

confidence: 99%

Thiols and the control of carbohydrate metabolism in cerebral tissues

McIlwain

1959

Biochemical Journal

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When cerebral tissues are incubated in glucosecontaining media, addition of glutathione increases their aerobic glycolysis. This has led to suggestions that glutathione plays a part in the Pasteur effect (Geiger, 1935; Baker, 1937; Weil-Malherbe, 1938). The tissues' respiration and glycolysis in glucosecontaining media are increased also by electrical pulses and by 20-100 mM-potassium salts, and these increases are smaller in the presence of cysteine (Mcllwain, 1954, and unpublished work). Cerebral respiration and glycolysis in vivo and in ordinary glucose media normally proceed at only

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Section: Respiration and Glycolysismentioning

confidence: 99%