Glycation and transglutaminase mediated glycosylation of fish gelatin peptides with glucosamine enhance bioactivity

Hong, Pui Khoon; Gottardi, Davide; Ndagijimana, Maurice; Betti, Mirko

doi:10.1016/j.foodchem.2013.07.045

Cited by 70 publications

(55 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3, fish gelatin films before heating showed excellent barrier properties against UV light due to the presence of peptide bonds (200-250 nm) and chromophores such as tyrosine and phenylalanine (250-300 nm)[21,22]. After heating, the formation of MRPs in the early stage is characterized by the increase of the absorption at 220 nm, related to the presence of carbonyl compounds, and the absorption around 280 nm, attributed to the presence of heterocyclic derivatives.…”

mentioning

confidence: 99%

Effects of cross-linking in nanostructure and physicochemical properties of fish gelatins for bio-applications

Etxabide

Urdanpilleta

Caba

2015

Reactive and Functional Polymers

View full text Add to dashboard Cite

mentioning

confidence: 99%

Effects of cross-linking in nanostructure and physicochemical properties of fish gelatins for bio-applications

Etxabide

Urdanpilleta

Caba

2015

Reactive and Functional Polymers

View full text Add to dashboard Cite

“…В частности, по-казано, что гликопротеины способны стимулировать CD4 + Т-клетки к синтезу рецепторассоциированных киназ (IL-2 и IL-4), что в свою очередь способствует образованию клона плазматических клеток, проду-цирующих антитела [73]. Например, гликозилиро-вание пептидов желатина из кожи рыб приводило к статистически значимому повышению их антиок-сидантной и антимикробной активности по сравне-нию с нативными пептидами [22].…”

Section: гликозилированные пептиды выделенные из морских гидробионтоunclassified

“…Гликозилирование пептидов желатина из кожи рыб приводит к статистически значимому повыше-нию их антиоксидантной и антимикробной активно-сти по сравнению с нативными пептидами [22].…”

Section: заключениеunclassified

Progress in using the drugs based on hydrobionts in treatment of respiratory viral infections and their complications

Katelnikova¹,

Макаров²,

Vorobieva

et al. 2017

Rev Clin Pharm Drug Ther

View full text Add to dashboard Cite

Ключевые слова:морские гидробионты; морские ежи; респираторные вирусные инфекции; противовирусная, противовоспалительная, антиок-сидантная активность пептидов и полисахаридов из морских ежей. РезюмеВ обзоре представлены сведения о возможности использова-ния биологически активных соединений, в частности пептидов и полисахаридов, из морских гидробионтов в качестве потен- Keywords:  sea hydrobionts; sea urchins; respiratory viral infections; antiviral; anti-inflammatory; antioxidant activity of peptides and polysaccharides from sea urchins. PROGRESS IN USING THE DRUGS BASED ON HYDROBIONTS IN TREATMENT OF RESPIRATORY VIRAL INFECTIONS AND THEIR COMPLICATIONS Abstract. The data of possibilities to use biologically active compounds, peptides and polysaccharides in particular, from sea urchins as potent sources of drugs are represented in the article. Their ability to act on the main chains of pathogenesis of the respiratory viral infections has been shown. So peptides and polysaccharides possess anti-inflammatory action due to inhibition of cyclooxygenase and inhibition of MAP kinase p38 phosphorylation, as well as antioxidant, immune correcting, antiviral and antibacterial effects. The progress in searching new drugs based on glycopeptides from sea urchins for treatment of respiratory tract infections and their complications are discussed.

show abstract

“…It is mainly used to treat osteoarthritis as a natural health product in Canada (Health Canada, 2017) or as a drug in the EU. Recently, GlcN have been used to modify different protein hydrolysates to produce taste-active, antioxidant and antimicrobial compounds (Hong et al, 2014; Hong et al, 2016; Gottardi et al, 2014). For instance, GlcN glycation of fish skin gelatin (Hong et al, 2014) or gluten (Gottardi et al, 2014) hydrolysates in the presence or absence of transglutaminase (TGase) enzyme resulted in an increased antimicrobial activity compared to the native hydrolysates.…”

Section: Introductionmentioning

confidence: 99%

Inhibitory activity of a Concanavalin-isolated fraction from a glucosamine-peptides reaction system against heat resistant E. coli

Hrynets

Martinez

Ndagijimana

et al. 2017

Heliyon

Self Cite

View full text Add to dashboard Cite

Alcalase-derived gelatin hydrolysates were glycated with glucosamine in the presence (+) or absence (−) of transglutaminase (TGase), and their antimicrobial activities toward Escherichia coli AW 1.7 were studied. Glycation treatments were subjected to concanavalin A affinity chromatography to selectively collect the glycopeptide-enriched fractions and the changes in antimicrobial activity were determined. The minimum inhibitory concentration of glycated hydrolysates decreased by 1.2 times compared to the native hydrolysate, with no differences between (+) or (−) TGase treatments. No difference was observed in the dicarbonyl compound concentration between the two glycation methods except that 3-deoxyglucosone was greater in the TGase-mediated reaction. Concanavalin A-retentate, but not the flow-through fractions, significantly improved the antimicrobial activity, however there was no difference between +TGase and −TGase glycated treatments. Purification of the retentate fraction from fluorescent compounds did not improve its antimicrobial activity.

show abstract

Glycation and transglutaminase mediated glycosylation of fish gelatin peptides with glucosamine enhance bioactivity

Cited by 70 publications

References 29 publications

Effects of cross-linking in nanostructure and physicochemical properties of fish gelatins for bio-applications

Effects of cross-linking in nanostructure and physicochemical properties of fish gelatins for bio-applications

Progress in using the drugs based on hydrobionts in treatment of respiratory viral infections and their complications

Inhibitory activity of a Concanavalin-isolated fraction from a glucosamine-peptides reaction system against heat resistant E. coli

Contact Info

Product

Resources

About