Glycemic Behavior in 48 Hours Postoperative Period of Patients With Type 2 Diabetes Mellitus and Non Diabetic Submitted to Bariatric Surgery

Abstract

Although there is no indication for surgery taking only into account the glycemic condition, results have shown that benefits can be obtained in glycemic control with bariatric surgery.Aim: To compare the glycemic behavior among type 2 diabetic and non-diabetic patients within 48 h after bariatric surgery, and clarify whether there is a reduction in blood glucose level in obese patients with diabetes before the loss of weight excess. Methods: Descriptive epidemiological study with prospective cohort design with 31 obese patients undergoing Roux-en-Y gastric bypass and sleeve gastrectomy. The patients were controlled with hemoglucotests in different periods of time: preoperative, postoperative and each 6 h after surgery for 48 h. Results: Average ambulatory blood glucose in diabetics was 120.7±2.9 mg/dl vs 91.8±13.9 mg/dl in the nondiabetic. After 48 h there was decrease in diabetics to 100.0±17.0 mg/dl (p=0.003), while the non-diabetic group did not change significantly (102.7±25.4 mg/dl; p=0.097). There were no differences between the surgical techniques. There were no death. Conclusions: Diabetic patients significantly reduced blood glucose after surgery regardless of the use of exogenous insulin or oral hypoglycemic agents.

Comparison of the Levels of C-Reactive Protein, GLP-1 and GLP-2 Among Individuals With Diabetes, Morbid Obesity and Healthy Controls: An Exploratory Study

“…Although these hormones have been identified in the early 1970s, they really rose to prominence after the growth of bariatric surgery and the observation of the critical impact of these procedures on their release and, consequently, on the glucose homeostasis and improvement of metabolic syndrome and its clinical features (16)(17)(18)(19)(20)(21)(22)(28)(29)(30)(31)(32)(33)(34) . In this study, we observed that the GLP-1 levels did not differ among non-diabetic individuals with morbid obesity, diabetic individuals with mild obesity and healthy controls.…”

Cirurgias bariátricas realizadas pelo Sistema Único de Saúde em residentes da Região Metropolitana de Porto Alegre, Rio Grande do Sul, 2010-2016*

“…2, [9][10][11] In 1999, gastroplasty was included among the procedures covered by the Brazilian National Health System (SUS). Currently, the criteria for the indication of surgery covered by the public network are (10,268) and South (9,734) regions were the ones that performed most surgeries at the public health system.…”

Effects of Long-Term Roux-en-Y Gastric Bypass on Body Weight and Clinical Metabolic Comorbidities in Bariatric Surgery Service of a University Hospital

“…Severe obesity patients are more likely to develop type 2 Diabetes Mellitus (DM2), high blood pressure (HBP) and dyslipidemia, among other diseases. To these individuals, as to those with body mass index (BMI) equal or lower than 35 kg/m² and that already have associated diseases, bariatric surgery is already being considered an important therapeutic alternative 9 , 20 .…”