Glycemic control and its association with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes in southwestern Nigeria

Abstract

Objective We determined the prevalence of poor glycemic control and associations with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes mellitus (T2DM) at a tertiary hospital in southwestern Nigeria. Methods We conducted a retrospective observational study among 300 patients with T2DM using systematic random sampling. We used a semi-structured questionnaire to collect information on respondents’ sociodemographic profile, lifestyle, comorbid conditions, and antidiabetic medications. Adherence was determined using the Morisky Medication Adherence Scale. Fasting blood samples were tested using a glycated hemoglobin marker. Multivariate logistic regression was used to identify factors associated with poor glycemic control. Results Respondents’ mean age was 61.9 ± 11.8 years. The prevalence of poor glycemic control was 40.0% (95% confidence interval [CI]: 34.4%–45.8%). The adjusted odds ratio (95% CI) for factors associated with poor glycemic control was 2.522 (1.402–4.647) for older age, 1.882 (1.021–3.467) for low income, 1.734 (1.013–3.401) for obesity, 2.014 (1.269–5.336) for non-initiation of insulin therapy, and 1.830 (1.045–3.206) for poor medication adherence. Conclusion Older age, lower income, obesity, non-initiation of insulin, and poor medication adherence were associated with poor glycemic control. These variables may help clinicians identify patients at high risk of poor glycemic control.

Medication adherence and its impact on glycemic control in type 2 diabetes mellitus patients with comorbidity: A multicenter cross-sectional study in Northwest Ethiopia

“…In line with previous studies [ 28 , 29 , 51 – 54 ], majority of patients were under poor glycemic control. Consistent with the previous studies [ 14 , 28 , 39 , 55 ], patients who had a low level of medication adherence were found more likely to have poor glycemic control. The findings may imply that poor glycemic control in the majority of Ethiopian population and settings might be related to low medication adherence.…”

“…In line with previous studies [28,29,[51][52][53][54], majority of patients were under poor glycemic control. Consistent with the previous studies [14,28,39,55], patients who had a low level of medication adherence were found more likely to have poor glycemic control. The…”

Medication adherence and its impact on glycemic control in type 2 diabetes mellitus patients with comorbidity: A multicenter cross-sectional study in Northwest Ethiopia

“…In line with previous studies (29,30,(51)(52)(53)(54), the majority of patients were under poor glycemic control. Consistent with the previous studies (14,29,39,55), patients who had a high level of medication adherence were found less likely to have poor glycemic control. Medication adherence of patients could maximize the effectiveness of pharmaceutical therapy.…”

A novel model forecasting perioperative red blood cell transfusion

“…Institutional review board approval was obtained (Singhealth CIRB2014/651/D) and all participants provided their written informed consent. In addition, we retrospective collected clinical data among 400 patients aged ≥ 18 years who underwent surgeries (except for transplantation, minor surgeries, and burning operations) using systematic random sampling 11 between 1 March 2021 and 30 June 2021 at Xiangya Hospital of Central South University. Surgical disciplines that were included cardiothoracic, orthopaedics, obstetrics and gynaecology, general surgery, otolaryngorhinology, hand surgery, neurosurgery, colorectal surgery, urology, plastic surgery, and oromaxillofacial surgery.…”