Glycine Crystallization in Solution by CW Laser-Induced Microbubble on Gold Thin Film Surface

Abstract

We have developed a novel laser-induced crystallization method utilizing local heat-induced bubble/water interface. Continuous laser beam of 1064 nm is focused on a gold nanoparticles thin film surface covered with glycine supersaturated aqueous solution. Light absorption of the film due to localized plasmon resonance caused local heating at the focal position and produced a single thermal vapor microbubble, which generated thermal gradient followed by convection flow around the bubble and eventually induced glycine crystallization and growth. The crystallization mechanism is discussed by considering gathering and accumulating molecules around the bubble/water interface assisted by convection flow and temperature jump.

A new experimental setup for high-throughput controlled non-photochemical laser-induced nucleation: application to glycine crystallization

“…Using NPLIN with a nanosecond pulsed laser, the form was produced unexpectedly (Zaccaro et al, 2001), and it was selectively produced using polarization (Garetz & Matić, 2002;Sun & Garetz, 2006) or with a femtosecond pulsed laser (Liu et al, 2013). Glycine has also been crystallized by NPLIN with a femtosecond CW laser (Rungsimanon et al, 2010;Uwada et al, 2012;Yuyama et al, 2012).…”

Nonphotochemical Laser-Induced Nucleation of Potassium Halides: Effects of Wavelength and Temperature

“…[3][4][5][6][7][8][9][10][11][12][13][14] Other methods include optical trapping or optically biased diffusion. [15][16][17][18][19][20][21][22] Recently, non-photochemical laser-induced nucleation (NPLIN) has been demonstrated, in which case there is no photochemical damage to the sample; 23,24 this effect has the potential to enable direct measurements of a nucleation process analogous to homogeneous nucleation.…”

Supersaturation dependence of glycine polymorphism using laser-induced nucleation, sonocrystallization and nucleation by mechanical shock

“…Uwada et al focussed a CW laser beam onto a gold surface submersed in supersaturated glycine solution. 29 The absorption of the beam by the film caused formation of a persistent vapour bubble. After a short time, a dense liquid was observed near the contact point between bubble and surface, followed by formation of a crystal.…”