Glycocalyx-mimetic dextran-modified poly(vinyl amine) surfactant coating reduces platelet adhesion on medical-grade polycarbonate surface

Gupta, Anirban Sen; Wang, S.; Link, Emily; Anderson, Eric H.; Hofmann, Christopher M.; Lewandowski, Jan; Kottke‐Marchant, Kandice; Marchant, Roger

doi:10.1016/j.biomaterials.2006.01.002

Cited by 60 publications

(53 citation statements)

References 52 publications

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“…Dextrans provide a stabilising coating for protecting metal nanoparticles against oxidation [23]. Dextran coating on biomaterials to prevent undesirable protein absorption is being explored to improve their biocompatibility [24]. Dextran therapy has side effects like anaphylaxis, volume overload, pulmonary oedema, cerebral oedema, acute renal failure and platelet dysfunction.…”

Section: Dextranmentioning

confidence: 99%

Potentials of Exopolysaccharides from Lactic Acid Bacteria

2011

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Recent research in the area of importance of microbes has revealed the immense industrial potential of exopolysaccharides and their derivative oligosaccharides from lactic acid bacteria. However, due to lack of adequate technological knowledge, the exopolysaccharides have remained largely under exploited. In the present review, the enormous potentials of different types of exopolysaccharides from lactic acid bacteria are described. This also summarizes the recent advances in the applications of exopolysaccharides, certain problems associated with their commercial production and the remedies.

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Section: Dextranmentioning

confidence: 99%

Potentials of Exopolysaccharides from Lactic Acid Bacteria

2011

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“…The cell glycocalyx is rich in glycosylated molecules, and the high resistance of this hydrated structure toward nonspecific interactions is a source of inspiration for biomimetic antifouling materials. Ruegsegger and Marchant (2001) developed glycocalyx-like materials based on oligomaltose with ability to resist protein and platelet adhesion, and have been followed by others (Ham et al 2013, Sen Gupta et al 2006.…”

Section: Introductionmentioning

confidence: 99%

Antifouling properties of oligo(lactose)-based self-assembled monolayers

et al. 2015

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The antifouling properties of oligo(lactose)-based self-assembled monolayers (SAMs), using four different proteins, zoospores of the green alga Ulva linza and cells of the diatom Navicula incerta, were investigated. The SAM-forming alkylthiols, which contained 1, 2 or 3 lactose units, showed significant variation in antifouling properties, with no differences in wettability.Non-specific adsorption of albumin and pepsin was low on all surfaces. Adsorption of lysozyme and fibrinogen decreased with increasing number of lactose units in the SAM, in agreement with the generally observed phenomenon that thicker hydrated layers provide higher barriers to protein adsorption. Settlement of spores of U. linza followed an opposite trend, being greater on the bulkier, more hydrated SAMs. These SAMs are more ordered for the larger saccharide units, and it is therefore hypothesized that the degree of order, and differences in crystallinity or stiffness between the surfaces, is an important parameter regulating spore settlement on these surfaces.

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“…Then, NaHA can be better adsorbed because of the electrostatic force between the carboxyl groups of NaHA and amino groups of MEA. Finally, we built an eleven-layer film (NaHA/ Chitosan) 5 NaHA. The fifth order frequency change is shown in Figure 2.…”

Section: Methodsmentioning

confidence: 99%

“…1 In order to get blood compatible surfaces, many studies focused on surface modification by imitating the endothelial surface layer (ESL). [2][3][4][5][6][7][8][9][10] The ESL is a three dimensional network composed of biomolecules lining the luminal surface of endothelial cells. [11][12][13] It is highly hydrated and forms a protective mechanical interface for the blood vessels and prevents adsorption of blood cells and other plasma molecules.…”

Section: Introductionmentioning

confidence: 99%

Theoretical and experimental study of the porous film using quartz crystal microbalance

Zhang

Tian

et al. 2016

Biomicrofluidics

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The self-assembled multilayers have been studied by many researchers to modify the surfaces of artificial implants for increasing biocompatibility. The accurate mechanical properties of the film can only be obtained from the experimental results using appropriate theoretical models. As the film is composed of both solid polymers and fluid, this paper proposes a two-phase model. Based on the volume average method, the momentum equations are derived for both solid and liquid phases. In order to test our model, we built the porous film on the gold chip of the quartz crystal microbalance using the layer-by-layer method. The buildup process is based on the electrostatic interactions between anionic sodium hyaluronate and cationic chitosan by imitating the endothelial surface layer. By fitting our model to the experimental changes of the resonant frequency and dissipation factor, we get reasonable values of the film thickness, the porosity, the shear modulus of the solid phase, and the permeability. Compared with the existing models, the newly introduced permeability is an important property of the porous layer affecting the values of other parameters. Our model can provide more intrinsic properties of the selfassembled polymeric network and explain its interaction with the permeating fluid. Published by AIP Publishing. [http://dx

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Glycocalyx-mimetic dextran-modified poly(vinyl amine) surfactant coating reduces platelet adhesion on medical-grade polycarbonate surface

Cited by 60 publications

References 52 publications

Potentials of Exopolysaccharides from Lactic Acid Bacteria

Potentials of Exopolysaccharides from Lactic Acid Bacteria

Antifouling properties of oligo(lactose)-based self-assembled monolayers

Theoretical and experimental study of the porous film using quartz crystal microbalance

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