Glycocinnamoylspermidines, a new class of antibiotics. 3. The structures of LL-BM123.beta., .gamma.1, and .gamma.2

Synthesis of Sugar Isocyanates and Their Application to the Formation of Ureido‐Linked Disaccharides

“…[10] A few glycosylureas have shown to be α-glycosidase inhibitors [11] and N-nitrosoureas, such as streptozotocin [12] and chlorozotocin, [13] possess antitumoral activity. [14] These substances induce crosslinking of DNA after in vivo decomposition.…”

Ferrocenylthiosemicarbazones conjugated to a poly(propyleneimine) dendrimer scaffold: Synthesis and in vitro antimalarial activity

“…In most cases they are found as conjugates with other biomolecules such as sugars [3], steroids [4], alkaloids [5], phospholipids [6] and peptides [7]. In addition, polyamines are involved in diverse biological processes including cell proliferation and differentiation, regulation of gene expression, translation, modulation of cell signalling and membrane stabilization [1,8,9].…”

Efficient Synthesis of Unsymmetrical Ureido‐Linked Disaccharides

“…[9,10] The glycosylϪurea bond is naturally widespread in glycocinnamoylspermidine antibiotics. [11,12] However, only a few methodologies for the formation of glycosylureas are described in the literature. The first methods employed the acid-catalyzed condensation of -glucopyranose with urea in water, [13] which was also used in the synthesis of symmetrical disaccharidic ureas, [14] the reaction of silver cyanate with glycosyl halides, [15] and the carbodiimide approach.…”