Glycoconjugates coated gold nanorods based novel biosensor for optical detection and photothermal ablation of food borne bacteria

Kaushal, Shimayali; Priyadarshi, Nitesh; Pinnaka, Anil Kumar; Soni, Sanjeev; Deep, Akash; Singhal, Nitin

doi:10.1016/j.snb.2019.03.096

Cited by 43 publications

(26 citation statements)

References 38 publications

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“…Figure 19 depicts the structure of compounds used to introduce carboxyl groups on AuNR. A characteristic that have in common is to include a terminal thiol function to create strong Au-S bonds and a carboxylic acid function at the other end, typically MUA [ 20 , 156 , 157 , 158 , 159 ], MHDA [ 160 , 161 ], or mercaptoPEG acid derivatives [ 162 , 163 , 164 , 165 , 166 , 167 ]. This general strategy has been applied to decorate AuNR with bioreceptors both in solution or once deposited on solid substrates (essentially glass slides) using the mercaptocarboxylic acids alone or in mixture with other thiols like mPEG-SH or 11-mercaptoundecanol in various proportions.…”

Section: Functionalization Methods Of Gold Nanorodsmentioning

confidence: 99%

“…Although antibodies and aptamers are the most commonly used bioreceptors for AuNR-LSPR biosensors, several less common biomolecules were also employed as summarized in Table 7 . AuNR-based biosensors using sugar bioreceptors were developed to assay food allergens [ 162 ] or the cancer biomarker galectin-1 [ 145 ]. AuNR-based genosensors were reported for the detection of pathogens [ 141 , 143 ].…”

Section: Applications Of Aunrs In Lspr Biosensingmentioning

confidence: 99%

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Gold Nanorods for LSPR Biosensing: Synthesis, Coating by Silica, and Bioanalytical Applications

Pellas

Mazouzi

et al. 2020

Biosensors

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Nanoparticles made of coinage metals are well known to display unique optical properties stemming from the localized surface plasmon resonance (LSPR) phenomenon, allowing their use as transducers in various biosensing configurations. While most of the reports initially dealt with spherical gold nanoparticles owing to their ease of synthesis, the interest in gold nanorods (AuNR) as plasmonic biosensors is rising steadily. These anisotropic nanoparticles exhibit, on top of the LSPR band in the blue range common with spherical nanoparticles, a longitudinal LSPR band, in all respects superior, and in particular in terms of sensitivity to the surrounding media and LSPR-biosensing. However, AuNRs synthesis and their further functionalization are less straightforward and require thorough processing. In this paper, we intend to give an up-to-date overview of gold nanorods in LSPR biosensing, starting from a critical review of the recent findings on AuNR synthesis and the main challenges related to it. We further highlight the various strategies set up to coat AuNR with a silica shell of controlled thickness and porosity compatible with LSPR-biosensing. Then, we provide a survey of the methods employed to attach various bioreceptors to AuNR. Finally, the most representative examples of AuNR-based LSPR biosensors are reviewed with a focus put on their analytical performances.

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Section: Functionalization Methods Of Gold Nanorodsmentioning

confidence: 99%

Section: Applications Of Aunrs In Lspr Biosensingmentioning

confidence: 99%

Gold Nanorods for LSPR Biosensing: Synthesis, Coating by Silica, and Bioanalytical Applications

Pellas

Mazouzi

et al. 2020

Biosensors

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“…Proteins on the bacterial surface are able to bind to different types of glycans on the host cells. Kaushal et al focused on a rapid detection of the food–borne pathogen E. coli with the application of gold nanorods-based sensors with good near-infrared absorption and scattering in surface plasmon resonance wavelength regions [ 91 ]. Polyethylene glycol-coated Au nanorods were immobilized by amine-terminated sugars—4-aminophenyl α-D-mannopyranoside and 4-aminophenyl β-D-galactopyranoside.…”

Section: Glycan-functionalized Nanoparticles (Nps)mentioning

confidence: 99%

“…E. coli bacteria bind to mannose-modified AuNPs and Pseudomonas aeruginosa was used as a control to check the aggregation of the galactose-modified nanorods. The assay was performed in a 96-well plate for a visible colorimetric detection [ 91 ].…”

Section: Glycan-functionalized Nanoparticles (Nps)mentioning

confidence: 99%

Glycan Nanobiosensors

et al. 2020

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This review paper comprehensively summarizes advances made in the design of glycan nanobiosensors using diverse forms of nanomaterials. In particular, the paper covers the application of gold nanoparticles, quantum dots, magnetic nanoparticles, carbon nanoparticles, hybrid types of nanoparticles, proteins as nanoscaffolds and various nanoscale-based approaches to designing such nanoscale probes. The article covers innovative immobilization strategies for the conjugation of glycans on nanoparticles. Summaries of the detection schemes applied, the analytes detected and the key operational characteristics of such nanobiosensors are provided in the form of tables for each particular type of nanomaterial.

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“…However, the requirement for pre-enrichment in non-selective culture broth, selective enrichment and plating, biochemical analysis and serological confirmation makes these methods labour-intensive and time-consuming, as the entire process can take several days [13,14]. In recent years, many efforts have been directed toward the development of new methods or techniques including immuno-based assays [15,16], polymerase chain reaction (PCR) [17], surface plasmon resonance (SPR) [18], flow cytometry (FC) [19] and loop-mediated isothermal amplification (LAMP) [20,21,22]. However, these methods entail multiple processing steps, hence increasing the risk of cross-contamination.…”

Section: Introductionmentioning

confidence: 99%

An Origami Paper-Based Device Printed with DNAzyme-Containing DNA Superstructures for Escherichia coli Detection

et al. 2019

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Rapid detection of pathogenic bacteria is extremely important for public health and safety. Here, we describe for the first time an integrated origami paper-based analytical device (PAD) incorporating cell lysis, molecular recognition, amplification and visual detection of Escherichia coli (E. coli). The device features three components: paper for its ability to extract protein molecules nonspecifically from cells, DNA superstructures for their ability to immobilize RNA-cleaving DNAzymes (RCDs) but undergo target-induced RNA cleavage on paper, and isothermal rolling circle amplification (RCA) for its ability to amplify each cleavage event into repetitive sequence units that can be detected by naked eye. This device can achieve detection of E. coli K12 with a detection limit of as low as 103 CFU·mL−1 in a total turnaround time of 35 min. Furthermore, this device allowed the sensitive detection of E. coli in complex sample matrices such as juice and milk. Given that more specific RCDs can be evolved for diverse bacteria, the integrated PAD holds great potential for rapid, sensitive and highly selective detection of pathogenic bacteria in resource-limited settings.

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Glycoconjugates coated gold nanorods based novel biosensor for optical detection and photothermal ablation of food borne bacteria

Cited by 43 publications

References 38 publications

Gold Nanorods for LSPR Biosensing: Synthesis, Coating by Silica, and Bioanalytical Applications

Gold Nanorods for LSPR Biosensing: Synthesis, Coating by Silica, and Bioanalytical Applications

Glycan Nanobiosensors

An Origami Paper-Based Device Printed with DNAzyme-Containing DNA Superstructures for Escherichia coli Detection

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