Glycopeptid-resistente Enterokokken in deutschen Krankenhäusern 1998

Klare, Ingo; Konstabel, Carola; Badstübner, D.; Werner, Guido; Witte, Wolfgang

doi:10.1007/978-3-662-38283-7_154

Cited by 1 publication

(2 citation statements)

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“…In Germany, rates of VRE colonization among the healthy adult population range between 0.9% and 12% [3,10]. In a recent study in mid-Europe, 2.2% of all enterococcal isolates were resistant to vancomycin [11].…”

Section: Discussionmentioning

confidence: 99%

“…Although in Europe the incidence of vancomycin-resistant enterococcus (VRE) among clinical isolates and the number of severe infections with VRE are still low, several outbreaks of invasive VRE infections in European hospitals have been reported [1][2][3]. To evaluate the current population-specific prevalence of VRE carriage among children and adolescents with end-stage renal failure (ESRF), we examined the perianal flora from 338 patients treated in 13 pediatric nephrology units in mid-Europe between April 1997 and January 1998.…”

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confidence: 99%

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Prevalence of Vancomycin‐Resistant Enterococci Among Children with End‐Stage Renal Failure

et al. 1999

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To evaluate the prevalence of colonization with vancomycin-resistant enterococcus (VRE) in end-stage renal failure (ESRF), we screened the intestinal flora from 338 pediatric ESRF patients treated in 13 pediatric nephrology units in mid-Europe. Eighty-one patients were undergoing hemodialysis, 66 were undergoing chronic peritoneal dialysis, and 191 were transplant recipients. A total of 363 enterococcal strains were recovered from 232 patients. Twenty-seven enterococcal strains from 24 patients (7.1%) had reduced susceptibility to vancomycin (minimal inhibitory concentration [MIC], >4 microg/mL). Although two patients (0.6%) carried enterococci with high-level resistance to vancomycin (MIC, >32 microg/mL; i.e., VRE), strains of enterococcus with reduced susceptibility to vancomycin (ERSV) were recovered from the other 22 subjects. Past use of vancomycin (P = .05) and tacrolimus therapy (P = .011) were independent risk factors for ERSV or VRE carriage. Enterococcal infections occurred with a similar frequency among enterococcal carriers and noncarriers; no infections with VRE or ERSV were reported. In conclusion, the prevalence of ERSV carriage and the rate of VRE colonization among mid-European children and adolescents with ESRF currently are moderate and low, respectively.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%