Glycyrrhiza glabra: Its role in dentistry

Hambire, Chaitali; Hambire, Umesh

doi:10.4103/srmjrds.srmjrds_94_19

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Results showed that hard candies with licorice extract and candies with xylitol extract yielded a higher mean percentage of change in streptococcus mutans count in terms of CFU in (baseline -14 days) interval and this may be attributed to the presence of alkaloids, tannins and essential oils in licorice root which prevent the adherence of bacteria to the tooth surfaces, inhibit the production of glucan and have inhibitory action on amylases. This is in accordance with the many studies (16,17) which also stated that glabridine one of the most important constituents of licorice root has a direct effect against both gram-positive strains and gram-negative strains. Moreover, the presence of glycyrrhizin, glycyrrhetinic acid, asparagine and chalcones in the licorice root extract improves its antiadhesive and antimicrobial properties.…”

Section: Discussionsupporting

confidence: 92%

“…A total number of 48 college students were selected from Faculty of Oral and Dental medicine, Ahram Canadian University. Inclusion criteria were systemically free college students of ages ranging from (16)(17)(18)(19)(20)(21)(22) years. Those students are high caries risk candidates defined according to CAMBRA (caries management by risk assessment) and they take candies as a daily sugary snack while following a moderate oral hygiene measures by brushing their teeth twice daily with a fluoridated tooth paste.…”

Section: Subject Selectionmentioning

confidence: 99%

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Evaluation of Antibacterial Effect of Different Sucrose Free Hard Candies in High-Risk Patients

2021

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Purpose: This study was conducted to evaluate the effect of four different hard candies on salivary Streptococcus mutans count and change in salivary pH in a group of Egyptian college students. Materials and Methods: Forty-eight healthy dental students, aged 16 -22 years were randomly allocated into 4 different study groups each of 12 students: sucrose free hard candies with licorice extract group, sucrose free hard candies with xylitol extract group, sucrose free hard candies group, and sucrose containing hard candies group (control). Unstimulated saliva was collected from the participants at baseline, following which the participants were given respective hard candies twice daily for 10 days and the subsequent salivary samples were collected at intervals of 14 days and 6 months. The samples were analyzed for Streptococcus mutans count in terms of CFU and pH using pH meter. Results: Regarding baseline -14 days interval, there was a statistically significant decrease in mean percentage change on bacterial count in licorice and xylitol group Moreover there was also a significant difference in salivary pH between different hard candies Conclusion: Addition of licorice or xylitol to sucrose free hard candies enhances its effect on streptococcus mutans and can shift salivary pH to a neutral value.

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Section: Discussionsupporting

confidence: 92%

Section: Subject Selectionmentioning

confidence: 99%

Evaluation of Antibacterial Effect of Different Sucrose Free Hard Candies in High-Risk Patients

2021

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“…It contains a multitude of phytocompounds such as liquirtin, isoliquertin liquiritigenin and rhamnoliquirilin, flavonoids (prenyllicoflavone A), and saponins (glycyrrhizic acid, glycyrrhizin) (Figure 7) [106]. In traditional medicine, G. glabra has many therapeutic effects, from antiviral, anti-tumor, anti-diabetic to antidepressant and antiepileptic [107], and in dentistry, it is used in the treatment of dental caries, gingival and periodontal diseases, oral candidiasis, oral cancer, and as an endodontic treatment [108]. Due to its glabridine content, G. glabra has strong antibacterial effects on both Gram-positive and-negative bacterial species.…”

Section: Herbs As Therapeutic Agents In Dentistrymentioning

confidence: 99%

Vegetal Compounds as Sources of Prophylactic and Therapeutic Agents in Dentistry

Milutinovici

Chioran

Buzatu

et al. 2021

Plants

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Dental pathology remains a global health problem affecting both children and adults. The most important dental diseases are dental caries and periodontal pathologies. The main cause of oral health problems is overpopulation with pathogenic bacteria and for this reason, conventional therapy can often be ineffective due to bacterial resistance or may have unpleasant side effects. For that reason, studies in the field have focused on finding new therapeutic alternatives. Special attention is paid to the plant kingdom, which offers a wide range of plants and active compounds in various pathologies. This review focused on the most used plants in the dental field, especially on active phytocompounds, both in terms of chemical structure and in terms of mechanism of action. It also approached the in vitro study of active compounds and the main types of cell lines used to elucidate the effect and mechanism of action. Thus, medicinal plants and their compounds represent a promising and interesting alternative to conventional therapy.

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Exploring the therapeutic potential of medicinal plants and their active principles in dental care: A comprehensive review

Refaey,

Abosalem,

Yasser El-Basyouni

et al. 2024

Heliyon

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Glycyrrhiza glabra: Its role in dentistry

Cited by 3 publications

References 11 publications

Evaluation of Antibacterial Effect of Different Sucrose Free Hard Candies in High-Risk Patients

Evaluation of Antibacterial Effect of Different Sucrose Free Hard Candies in High-Risk Patients

Vegetal Compounds as Sources of Prophylactic and Therapeutic Agents in Dentistry

Exploring the therapeutic potential of medicinal plants and their active principles in dental care: A comprehensive review

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