“…Very few nano-formulations have been prepared and studied for phytochemicals such as genistein (Nguyen et al,2015;Jackson et al, 2017;Kim et al, 2017;Pool et al, 2018), rosmarinic acid (Madureira et al, 2016;Ezzat et al, 2016), huperzine A (Meng et al, 2018), ginkgolide (Feng et al, 2018;Lou et al, 2019), ginsenoside (Kim et al, 2016;Aalinkeel et al, 2018;Dai et al, 2018) andβ-Sitosterol (El-Nahas et al, 2017;Gogoi et al, 2018;Ponnulakshmi et al, 2019). As stated, few phytochemicals are not synthesized as a nanoformulation (Venkatesan et al, 2016, Venkatesan et al, 2017, Encinas-Basurto et al, 2018, Hosokawa et al, 2018Sarrica et al, 2018). Additionally, reviewed the regulatory perspective of registry for the NPs focused in streamlining the synthesis and the NPs disposal norms (Weiss-Angeli et al, 2012;Hansen et al, 2017;Zainon and Azmi, 2021).…”