Goat and Bovine Colostrum as a Basis for New Probiotic Functional Foods and Dietary Supplements

Hyršlová, Ivana; Krausová, Gabriela; Bartova, Jirina; Kolesár, Libor; Čurda, L.

doi:10.4172/1948-5948.1000262

Cited by 13 publications

(5 citation statements)

References 18 publications

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“…The composition and characteristics of colostrum are different from milk. Colostrum is a rich source of essential nutrients and its use in functional foods and food supplements has received substantial considerations (Ceniti et al, 2019;Hyrslova et al, 2016;Silva et al, 2019). Bioactive components of colostrum include growth factors, immunoglobulins, lysozyme, lactoferrin, oligosaccharides, and some immunomodulatory peptides (Hyrslova et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…Colostrum is a rich source of essential nutrients and its use in functional foods and food supplements has received substantial considerations (Ceniti et al, 2019;Hyrslova et al, 2016;Silva et al, 2019). Bioactive components of colostrum include growth factors, immunoglobulins, lysozyme, lactoferrin, oligosaccharides, and some immunomodulatory peptides (Hyrslova et al, 2016). Time of milking determines the concentration of bioactive components; for example Ceniti et al (2019) reported that immunoglobulins in colostrum decreased from 93.36 g/L to 5.53 g/L in 48 hours.…”

Section: Introductionmentioning

confidence: 99%

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Improving composition and microbiological characteristics of milk kefir using colostrum

et al. 2020

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Kefir characteristics are influenced by raw materials. Fresh milk and colostrum have different characteristics. In this research, colostrum was used as additional material in kefir production which could affect the chemical, microbiological, and antimicrobial properties of final the product. This study was aimed to investigate the chemical and microbiology properties of kefir prepared from milk, colostrum and milk-colostrum mixes. Kefir was prepared by adding kefir grains to 100% fresh milk, milk-colostrum mixes (20:80%; 40:60%; 60:40%; 80:20%) and 100% colostrum. Fermentation was allowed under room temperature for 24 hours. Results showed that all treatments produced kefir with relatively similar titrable acidity, free fatty acids, and fat contents. The highest levels of ethanol, total solids and protein content were observed in kefir produced from 100% colostrum. The average total microbes were 6.37-7.51 log CFU/ml; 7.04-8.23 log CFU/ml bacteria; 6.92-7.48 log CFU/ml LAB and 5.54-6.55 log CFU/ml yeast. Water activity values ranged from 0.85 to 0.89. The highest microbial and antimicrobial properties were shown by kefir produced from milk-colostrum mix of 20:80%.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Improving composition and microbiological characteristics of milk kefir using colostrum

et al. 2020

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“…Colostrum is the composition of immunoglobulins, minerals and other biological substances which transfer form colostrum to the young ones [58]. The quality of the colostrum depends upon maternal nutrition [59,60]. The diet supplemented with phytobiotics has been assumed to be the main source of managing nutrition-induced oxidative stress in pregnancy and lactation in livestock [45,46,61].…”

Section: Oxidative Stress During Lactation and Antioxidantsmentioning

confidence: 99%

Antioxidant Strategies to Improve Female Reproduction

Hussain¹

2023

Biochemistry

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Animals are only productive once their reproductive cycle is continuously flown. There are several causes of stresses which interrupt animal physiology and make animal less productive. All factors involved in stress could eventually generate reactive oxygen species (ROS). Limited production of these reactive species performs several functions to maintain redox homeostasis. When these reactive oxidative metabolites are overwhelmed, it may generate oxidative stress. Disruption in oxidant/antioxidant mechanism leads to cause oxidative stress. Naturally, the body system is equipped with an antioxidant defense system. Once this system is broken-down due to the overproduction of ROS, it may have a detrimental effect on lipids, proteins, DNA, and carbohydrates and eventually influence animal fertility and productivity. Antioxidants available in nature are of two types: natural and synthetic. These compounds endowed several properties in the mitigation of various animal stresses, starting from physiology to molecular level. This chapter elucidates oxidative stress, natural and synthetic antioxidants, and particular focus are emphasized that how antioxidant supplementation can help to improve animal fertility and productivity. Moreover, the mechanism by which antioxidants produce fruitful effects will also be highlighted.

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“…Colostrum or first milk is secreted by all female mammals, including women, during the first four days after parturition and is provided to their neonates during the initial 24-48 hours after birth (Bagwe et al, 2015;Agarwal and Gupta, 2016;Hyrslova et al, 2016;Jolly and Mascaro, 2016;Buttar et al, 2017). Colostrum is thick, sticky, yellowish liquid which not only provides nutrition and immunity but also gives protection against microbial infections.…”

Section: Cancermentioning

confidence: 99%

Therapeutic Applications of Human and Bovine Colostrum in the Treatment of Gastrointestinal Diseases and Distinctive Cancer Types: The Current Evidence

et al. 2020

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The incidence of gastrointestinal disorders (GID) and cancers is escalating all over the world. Limited consumption of colostrum by newborns not only weakens the immune system but also predisposes infants to microbial infections. Colostrum is nature’s perfect food, sometimes referred to as the ‘elixir of life’. Breast-fed infants have a lower incidence of GI tract infections than infants fed formula or cow’s milk. As per WHO statistics, cancer is the most prevalent disease globally and causes 9.6 million deaths worldwide. The current strategies for treating cancer include chemotherapy, radiation, and surgery. However, chemotherapy and radiation exposure are usually associated with serious long-term side effects and deterioration in the quality of life (QOL) of patients. Furthermore, the hospitalization and medication costs for treating cancers are exorbitant and impose high economic burden on healthcare systems. People are desperately looking for cost-effective and affordable alternative therapies for treating GID and cancers. Therefore, there is an urgent need for clinically evaluating the anticancer compounds isolated from plants and animals. Such therapies would not only be economical and have fewer side effects, but also help to improve the QOL of cancer patients. Recently, bovine colostrum (BC) has caught the attention of many investigators to explore its anticancer potential in humans. BC impregnated dressings are highly effective in treating chronic wounds and diabetic foot ulcer. BC is rich in lactoferrin, a glycoprotein with strong antioxidant, anti-inflammatory, anti-cancer, and anti-microbial properties. Intravaginal application of BC tablets is effective in causing the regression of low-grade cervical intraepithelial neoplasia. The underlying mechanisms of BC at cellular, genetic, and molecular levels remain to be ascertained. Oral BC supplement is well-tolerated, but some people may experience problems such as flatulence and nausea. Well-designed, randomized, placebo-controlled, clinical trials are needed to access the therapeutic potential, long-term safety, and optimal doses of BC products. This review is aimed to highlight the anticancer potential of BC and its components, and the therapeutic applications of BC supplements in treating gastrointestinal diseases in children and adults. We also discuss the health promotion benefits and therapeutic potential of BC nutraceuticals in reducing the incidence of non-communicable diseases.

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Goat and Bovine Colostrum as a Basis for New Probiotic Functional Foods and Dietary Supplements

Cited by 13 publications

References 18 publications

Improving composition and microbiological characteristics of milk kefir using colostrum

Improving composition and microbiological characteristics of milk kefir using colostrum

Antioxidant Strategies to Improve Female Reproduction

Therapeutic Applications of Human and Bovine Colostrum in the Treatment of Gastrointestinal Diseases and Distinctive Cancer Types: The Current Evidence

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