Goitre amyloïde : première manifestation d’une amylose systémique

Chraibi, A.; Msyah, L.; Laaribi, O.; Marrakchi, A.; Hafidi, A.

doi:10.1016/j.ando.2007.10.002

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Both patients were underwent thyroidectomy to alleviate pressure symptoms and were both ensured for follow-up for fear of appearance of malignancies especially plasma cell tumours and lymphoma in case 1 and for fear of deterioration of renal functions in case 2. It is reported that AG may appear before or after the clinical appearance of the overt malignancy and before other system affection [7].…”

Section: Discussion and Review Of Literaturementioning

confidence: 99%

“…It occurs in about 50% to 70% of medullary thyroid carcinoma, secondary to long standing inflammatory conditions such as rheumatoid arthritis [2], cystic fibrosis [3] [4], ankylosing sponilitis [5] and Crohn's disease [6]. AG may also be secondary to long standing chronic infectious inflammatory diseases such as bronchiectasis [7] and tuberculosis [8]. The condition was reported in association with renal failure [9], nephritic syndrome [10] and familial Mediterranean fever (FMF) [11].…”

Section: Introductionmentioning

confidence: 99%

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Amyloid Goiter: Clinicopathological Assessment of Two Cases and Review of Literature

Mohammed¹,

Yassin²,

Radwan³

et al. 2015

OJPathology

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Amyloid goiter (AG) is a rare but well-established disease entity that may occur in a number of conditions. In the following article, we will report two cases of AG. Both patients were young males: 28 & 24 years old, presented with rapidly enlarging thyroid gland manifested with pressure effects (dyspnea and hoarseness of voice). Provisional clinical diagnosis was malignant thyroid neoplasm. One of the patients was markedly hypothyroid while the other was euthyroid. Histopathological evaluation revealed extracellular deposition of deep pink homogenous material that was confirmed as amyloid with congo red. Patient in case 1 was primary localized AG while patient in case 2 was systemic amyloidosis secondary to interstitial pulmonary fibrosis (IPF) that was first manifested by AG. The main aims of the article were to describe histopathological features of amyloidosis of the thyroid gland and to raise awareness of AG to be included in the differential diagnosis in patients presented with rapidly enlarging goiter with mass effects.

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Section: Discussion and Review Of Literaturementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Amyloid Goiter: Clinicopathological Assessment of Two Cases and Review of Literature

Mohammed¹,

Yassin²,

Radwan³

et al. 2015

OJPathology

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A Case of Amyloid Goiter Associated with Intrathyroid Parathyroid and Lymphoepithelial Cyst

Abdou

Kandil

2009

Endocr Pathol

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Diffuse enlargement of the thyroid gland accompanied by an interstitial tissue deposition of amyloid is a special entity termed an amyloid goiter. An amyloid goiter is a rare thyroid lesion, which has been described a long time ago. In this report, we add a new classic case of amyloid goiter that differs from other reported cases in its association with intrathyroid parathyroid and lymphoepthelial cyst involved with amyloidosis. The presence of parathyroid tissue inside the thyroid parenchyma and surrounded by amyloid material elicited a diagnostic problem due to suspected medullary carcinoma. Careful histological examination and immunohistochemical staining for parathormone and calcitonin have largely helped in the differential diagnosis. Bilaterality, diffuse, and homogeneous involvement of the thyroid gland, with absence of definite masses, all direct the diagnosis toward amyloid goiter.

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Amyloid Goiter Secondary to Ulcerative Colitis

Aydın

Koca

et al. 2016

Case Reports in Endocrinology

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Diffuse amyloid goiter (AG) is an entity characterized by the deposition of amyloid in the thyroid gland. AG may be associated with either primary or secondary amyloidosis. Secondary amyloidosis is rarely caused by inflammatory bowel diseases. Secondary amyloidosis is relatively more common in the patients with Crohn's disease, whereas it is highly rare in patients with ulcerative colitis. Diffuse amyloid goiter caused by ulcerative colitis is also a rare condition. In the presence of amyloid in the thyroid gland, medullary thyroid cancer should be kept in mind in the differential diagnosis. Imaging techniques and biochemical tests are not very helpful in the diagnosis of secondary amyloid goiter and the definitive diagnosis is established based on the histopathologic analysis and histochemical staining techniques. In this report, we present a 35-year-old male patient with diffuse amyloid goiter caused by secondary amyloidosis associated with ulcerative colitis.

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Goitre amyloïde : première manifestation d’une amylose systémique

Cited by 3 publications

References 8 publications

Amyloid Goiter: Clinicopathological Assessment of Two Cases and Review of Literature

Amyloid Goiter: Clinicopathological Assessment of Two Cases and Review of Literature

A Case of Amyloid Goiter Associated with Intrathyroid Parathyroid and Lymphoepithelial Cyst

Amyloid Goiter Secondary to Ulcerative Colitis

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