Gold Contact Allergy

Abstract

In 2001, gold was named Contact Allergen of the Year. More than a decade later, we continue to face several challenges in defining the role of gold in contact allergy. First, interpretation of gold reactions in the setting of epicutaneous patch testing may be difficult; in addition to being a common irritant, gold may be associated with significantly delayed and persistent reactions. Second, although gold compounds are commonly positive on patch testing, clinical relevance is relatively low and may be challenging to determine. Third, the complex interplay between gold and the human body is still poorly understood. In this review, we provide an overview of the literature concerning gold patch test positivity and present recommendations for epicutaneous patch testing with gold.

Metals Are Important Contact Sensitizers: An Experience from Lithuania

“…Compared to other countries Lithuania is leading in gold sensitization (Table 2). It is often very difficult to find clinical relevance of positive reaction [15]. It was an overrepresentation of face dermatitis in the group of patients with gold allergy although we did not find direct causal relationship to gold allergy.…”

Alergias en la atención dental

“…El oro se utiliza principalmente en restauraciones posteriores 4 , y se ha descrito que es el alérgeno más común después del níquel 3 . Las reacciones liquenoides orales son la manifestación más frecuente de hipersensibilidad 4,23 . También se ha asociado a estomatitis alérgica de contacto, queilitis, dermatitis perioral, ardor y ulceración de la mucosa 23 .…”

“…Las reacciones liquenoides orales son la manifestación más frecuente de hipersensibilidad 4,23 . También se ha asociado a estomatitis alérgica de contacto, queilitis, dermatitis perioral, ardor y ulceración de la mucosa 23 .…”

All that is gold does not glitter: Systemic allergic dermatitis and massive skin and muscle oedema following genicular artery embolisation with (Embo)gold

“…Different embolising agents can be used, including Embogold (Merit Medical Systems, South Jordan, UT), a medical device consisting of acrylic polymer microspheres impregnated with porcine gelatin and 2% gold 2 . Gold is a well‐known sensitiser that may provoke allergic contact dermatitis (ACD) and occasionally also systemic allergic dermatitis (SAD) 3,4 . Herein, we report two patch test documented patients with cutaneous adverse events from gold in Embogold.…”