Gold nanobipyramids integrated ultrasensitive optical and electrochemical biosensor for Aflatoxin B1 detection

Bhardwaj, Hema; Sumana, Gajjala; Marquette, Christophe A.

doi:10.1016/j.talanta.2020.121578

Cited by 41 publications

(13 citation statements)

References 36 publications

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“…Marquette et al developed electrical and optical biosensing for label-free detection of Aflatoxin B1 (AFB1) using gold (Au) nanobipyramids (NBPs). SPR-based AFB 1 detection was found to be in the linear range of 0.1-500 nM with a detection limit of 0.4 nM, while impedimetric AFB 1 detection was exhibited in the linear range of 0.1-25 nM, having a detection limit of 0.1 nM [49].…”

Section: Antibody-based Biosensorsmentioning

confidence: 93%

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Naresh

Lee

2021

Sensors

1,089

427

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A biosensor is an integrated receptor-transducer device, which can convert a biological response into an electrical signal. The design and development of biosensors have taken a center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications, such as health care and disease diagnosis, environmental monitoring, water and food quality monitoring, and drug delivery. The main challenges involved in the biosensor progress are (i) the efficient capturing of biorecognition signals and the transformation of these signals into electrochemical, electrical, optical, gravimetric, or acoustic signals (transduction process), (ii) enhancing transducer performance i.e., increasing sensitivity, shorter response time, reproducibility, and low detection limits even to detect individual molecules, and (iii) miniaturization of the biosensing devices using micro-and nano-fabrication technologies. Those challenges can be met through the integration of sensing technology with nanomaterials, which range from zero- to three-dimensional, possessing a high surface-to-volume ratio, good conductivities, shock-bearing abilities, and color tunability. Nanomaterials (NMs) employed in the fabrication and nanobiosensors include nanoparticles (NPs) (high stability and high carrier capacity), nanowires (NWs) and nanorods (NRs) (capable of high detection sensitivity), carbon nanotubes (CNTs) (large surface area, high electrical and thermal conductivity), and quantum dots (QDs) (color tunability). Furthermore, these nanomaterials can themselves act as transduction elements. This review summarizes the evolution of biosensors, the types of biosensors based on their receptors, transducers, and modern approaches employed in biosensors using nanomaterials such as NPs (e.g., noble metal NPs and metal oxide NPs), NWs, NRs, CNTs, QDs, and dendrimers and their recent advancement in biosensing technology with the expansion of nanotechnology.

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Section: Antibody-based Biosensorsmentioning

confidence: 93%

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Naresh

Lee

2021

Sensors

1,089

427

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“…This EC aptasensor exhibited a lower LOD (3.4 pg mL À 1 ) over a wider range (10-50,000 pg mL À 1 ) than chemiluminescence ELISA (LOD: 120 pg mL À 1 ) [94]. Bhardwaj et al [95] developed an ultrasensitive integrated immunosensor for AFB1 using optical and EIS detection, where ITO substrates were modified by Au NP and Au nanobipyramids, provided sensitive AFB1 detection (LOD: 0.1 nM) in maize samples.…”

Section: Impedance Sensor For Mycotoxin Detectionmentioning

confidence: 96%

Recent Advances in Electrochemical Sensors for Mycotoxin Detection in Food

Chen

Tang

et al. 2021

Electroanalysis

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Mycotoxins pose a grave global threat to human life and health by contaminating food and feed and cause enormous losses in healthcare and trading. Trace mycotoxin concentrations and diverse matrices in food make identification and measurement challenges, necessitating highly specific and sensitive detection methods. Electrochemical (EC) sensors are characterized by simple operation, outstanding sensitivity, low cost, and facile miniaturization and have become a promising strategy for addressing specificity and sensitivity in detection. Recent studies on EC sensors for mycotoxin detection for food safety are reviewed here. First, we summarize the fabrication of EC sensors and techniques with enhanced specificity and sensitivity. Then, we review state‐of‐the‐art EC sensors for detecting major mycotoxins. Challenges and opportunities for this technology are further discussed. Finally, in‐depth information is provided on using EC sensors to detect mycotoxins for food safety, as well as the development of EC sensors for academic study and practical application.

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“…[79] By contrast, labeled /indirect immunosensors use a detectable label (an enzyme or fluorescent molecule), being the immunocomplex sensitively determined through the measurement of the label (Figure 4b). [81][82][83]8]…”

Section: Functionalization Of Naamentioning

confidence: 99%

Oligonucleotic Probes and Immunosensors Based on Nanoporous Anodic Alumina for Screening of Diseases

Xifré-Pérez

Ferré‐Borrull

Marsal

2022

Adv Materials Technologies

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This paper is an overview of the recent advances in nanoporous anodic alumina sensing platforms based on the interaction of oligonucleotides and antibodies with bioelements (e.g., virus, bacteria, or biomarkers) that can cause or identify diseases. Nanoporous alumina is the common platform material for all these sensing devices that have an enormous potential for the next‐generation bioanalytical systems. Nanoporous alumina is a cost‐effective material with morphological flexibility that provides high sensitivity to the sensing systems due to its large surface‐to‐volume ratio. Immunosensors transduce the signal produced by the specific antibody–antigen interaction. They are widely used for clinical analysis due to the high selectivity and sensitivity of their immunoreaction, transduced by different methods (electrochemical, optical, piezoelectric, etc). Another important, outstanding and more recently type of biosensors are based on the oligonucleotic functionalization of nanoporous alumina. Oligonucleotides can bind to a wide variety of elements (small organic molecules, proteins, or cells) with high selectivity, specificity, and affinity, even higher to those of antibodies. The basic concepts and mechanisms of their sensing methods for health care biosensing are introduced. Their transduction methods and great potential applications will be evaluated and classified in detail, together with a discussion of possible future trends.

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Gold nanobipyramids integrated ultrasensitive optical and electrochemical biosensor for Aflatoxin B1 detection

Cited by 41 publications

References 36 publications

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Recent Advances in Electrochemical Sensors for Mycotoxin Detection in Food

Oligonucleotic Probes and Immunosensors Based on Nanoporous Anodic Alumina for Screening of Diseases

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