Gold Nanoparticle-Biological Molecule Interactions  and Catalysis

Heddle, Jonathan G.

doi:10.3390/catal3030683

Cited by 30 publications

(20 citation statements)

References 161 publications

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“…99 Devido à promoção de interações químicas específicas e seletivas, muitos conectores são à base de biomoléculas (proteínas, peptídeos, filamentos da cadeia do DNA etc.). 100,101 Em particular, a automontagem induzida pelo uso de DNA como agente modificador de superfície de nanopartículas tem se tornado uma ferramenta poderosa na formação de arranjos nanoestruturados altamente organizados (Figura 12). 102,103…”

Section: Funcionalização De Superfície De Nanopartículas Com Moléculaunclassified

Self-Assembly of Metal Nanoparticles, an Important Process to the Development of New Nanostructured Materials and Devices

Oliveira¹,

Bezerra²,

Silva³

et al. 2020

Rev. Virtual Quim.

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The growing interest of researchers in the development of nanomaterials can be measured by the large number of articles and patents that have been published in recent years. In particular, inorganic, organic or even hybrid nanoparticles of different sizes and shapes are already synthesized in a very controlled manner and without very elaborated experimental conditions. However, despite the advances, much work remains to be done on the use of nanoparticles as building blocks for the generation of new nanostructured materials and devices. Actual manipulation of nanoparticles for the construction of a particular device has many limits and usually requires high cost and high technology equipment. However, a promising strategy that can lead to the formation of nanostructured arrangements in a very controlled manner is based on nanoparticle self-assembly processes. Directed particle self-assembly can be described as a planned, controlled and organized aggregation of the particles to obtain a specific particles arrangement or device. Self-assembling material not only serves to generate a structure itself, but also to achieve unique chemical and physical properties in the material that arise only due to the arrangement and interactions between the nanoparticulates. Due to the importance of this subject for the development of nanotechnology products, this article shows, through a broad and generalized approach, some of the most common methods found in the specialized literature about self-assembling of metallic nanoparticles. O crescente interesse de pesquisadores no desenvolvimento de nanomateriais pode ser medido pelo grande número de artigos e patentes que vêm sendo publicados nos últimos anos. Particularmente, nanopartículas inorgânicas, orgânicas ou mesmo híbridas, das mais variadas formas e tamanhos, já são sintetizadas de maneira bastante controlada e sem condições experimentais muito elaboradas. Entretanto, apesar dos avanços, ainda há muito trabalho por ser realizado quanto ao emprego de nanopartículas como blocos de construção para a geração de novos materiais e dispositivos nanoestruturados. A real manipulação de nanopartículas para a construção de um determinado dispositivo apresenta muitos limites e geralmente requer equipamentos de elevado custo e alta tecnologia. Contudo, uma estratégia promissora que pode levar à formação de arranjos nanoestruturados de maneira bastante controlada baseia-se em processos de automontagem de nanopartículas. A automontagem planejada de partículas pode ser descrita com uma agregação planificada, controlada e organizada das mesmas para a obtenção de um arranjo ou dispositivo. O material obtido por automontagem não serve apenas para a geração de uma estrutura em si, mas também para alcançar propriedades químicas e físicas singulares no material que se manifestam apenas devido ao arranjo e a interação entre seus componentes nanoparticulados. Devido à importância desse tema para o desenvolvimento de produtos nanotecnológicos, este artigo de revisão mostra, através de uma abordagem ...

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Section: Funcionalização De Superfície De Nanopartículas Com Moléculaunclassified

Self-Assembly of Metal Nanoparticles, an Important Process to the Development of New Nanostructured Materials and Devices

Oliveira¹,

Bezerra²,

Silva³

et al. 2020

Rev. Virtual Quim.

View full text Add to dashboard Cite

show abstract

“…Au nanoparticles (AuNPs) and graphene assemble platform was used for the modification on the electrode surface, which can improve the electronic transmission rate as well as increase the surface area. XNA probes combined nanoparticles was used for signal amplification label, coupled with complementary ssDNA and decorated with electroactive substance (Heddle, ; Howes, Rana, & Stevens, ).…”

Section: Commonly Used Signaling Modes Of Xna Probes In Paper‐based Poctmentioning

confidence: 99%

Paper‐based point‐of‐care test with xeno nucleic acid probes

Xiao

Jin

et al. 2019

Biotech & Bioengineering

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Bridging the unmet need of efficient point-of-care testing (POCT) in biomedical engineering research and practice with the emerging development in artificial synthetic xeno nucleic acids (XNAs), this review summarized the recent development in paperbased POCT using XNAs as sensing probes. Alongside the signal transducing mode and immobilization methods of XNA probes, a detailed evaluation of probe performance was disclosed. With these new aspects, both researchers in synthetic chemistry / biomedical engineering and physicians in clinical practice could gain new insights in designing, manufacturing and choosing suitable reagents and techniques for POCT. K E Y W O R D S aptamer, chemical modification, paper-based analytical devices (PADs), point-of-care testing (POCT), xeno nucleic acids (XNAs)

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“…Recently, a special attention has been paid to the synthesis of gold nanoparticles (Au NPs) that may be used in medicine (Butle and Baheti 2011 ), genomics (Larguinho and Baptista 2012 ), biology (Heddle 2013 ), cosmetology (Saha et al 2011 ), and optics (Fischer et al 2012 ) due to their respective chemical (Giljohann et al 2010 ), physical (Xia et al 2009 ), therapeutic (Lan et al 2013 ), and electronic (Bastús et al 2011 ) properties.…”

Section: Introductionmentioning

confidence: 99%

The influence of stabilizers on the production of gold nanoparticles by direct current atmospheric pressure glow microdischarge generated in contact with liquid flowing cathode

et al. 2015

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Gold nanoparticles (Au NPs) were prepared by direct current atmospheric pressure glow microdischarge (dc-μAPGD) generated between a miniature argon flow microjet and a flowing liquid cathode. The applied discharge system was operated in a continuous flow liquid mode. The influence of various stabilizers added to the solution of the liquid cathode, i.e., gelatin (GEL), polyvinylpyrrolidone (PVP), or polyvinyl alcohol (PVA), as well as the concentration of the Au precursor (chloroauric acid, HAuCl4) in the solution on the production growth of Au NPs was investigated. Changes in the intensity of the localized surface plasmon resonance (LSPR) band in UV/Vis absorption spectra of solutions treated by dc-μAPGD and their color were observed. The position and the intensity of the LSPR band indicated that relatively small nanoparticles were formed in solutions containing GEL as a capping agent. In these conditions, the maximum of the absorption LSPR band was at 531, 534, and 535 nm, respectively, for 50, 100, and 200 mg L−1 of Au. Additionally, scanning electron microscopy (SEM) and dynamic light scattering (DLS) were used to analyze the structure and the morphology of obtained Au NPs. The shape of Au NPs was spherical and uniform. Their mean size was ca. 27, 73, and 92 nm, while the polydispersity index was 0.296, 0.348, and 0.456 for Au present in the solution of the flowing liquid cathode at a concentration of 50, 100, and 200 mg L−1, respectively. The production rate of synthesized Au NPs depended on the precursor concentration with mean values of 2.9, 3.5, and 5.7 mg h−1, respectively.

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Gold Nanoparticle-Biological Molecule Interactions and Catalysis

Cited by 30 publications

References 161 publications

Self-Assembly of Metal Nanoparticles, an Important Process to the Development of New Nanostructured Materials and Devices

Self-Assembly of Metal Nanoparticles, an Important Process to the Development of New Nanostructured Materials and Devices

Paper‐based point‐of‐care test with xeno nucleic acid probes

The influence of stabilizers on the production of gold nanoparticles by direct current atmospheric pressure glow microdischarge generated in contact with liquid flowing cathode

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