Gold Nanoparticle Biosynthesis by E. coli and Conjugation with Streptomycin and Evaluation of its Antibacterial Effect

Mazdeh, Samaneh Khademi; Motamedi, Hossein; Khiavi, Azim Akbarzadeh; Mehrabi, Mohammad Reza

doi:10.2174/1573413709666131203231344

Cited by 10 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In recent years, the vigorous development of green chemistry has promoted the preparation of gold nanoplates by biological method [24]. Biomass such as lemongrass, aloe vera, seaweed, alfalfa, E. coli and Platycladus orientalis extract has been used as reductive and protective agents to synthesize gold nanoplates [25,26]. For example, Shankar et al [27] developed a biological method to produce up to 45% gold nanoplates by citronella leaf extract.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Gold Nanoplates Using Ortho Carbonyl Compounds as Capping Agents for Electrochemical Sensing of Lead Ions

Jiang

et al. 2021

Nanoscale Res Lett

View full text Add to dashboard Cite

In this study, gold nanoplates were synthesized using plant molecules (gallic acid) following a kinetic control mode. The growth of nanoplates is mainly due to the specific adsorption of capping agents on certain crystal facets. Through systematical characterizations, it is found that the distance between two oxygen atoms in ortho carbonyl compounds matches well with the lattice spacing of gold (111) facets exactly, which is beneficial to the formation of twin seeds and further the growth of plate-like gold nanoparticles. The gold nanoplates on glassy carbon electrode show a remarkably improved electrochemical sensing activity of lead ions compared to the bare glassy carbon electrode or spherical gold nanoparticle-modified electrode. The modified electrode is expected to be used in the detection of lead ion concentration in heavy metal wastewater.

show abstract

Section: Introductionmentioning

confidence: 99%

Preparation of Gold Nanoplates Using Ortho Carbonyl Compounds as Capping Agents for Electrochemical Sensing of Lead Ions

Jiang

et al. 2021

Nanoscale Res Lett

View full text Add to dashboard Cite

show abstract

“…The biogenic AuNPs were also employed for the synthesis of antibiotic functionalized AuNPs . The AuNPs synthesized using E. coli cells were functionalized with streptomycin and observed to have a significant reduction in MIC/MBC to 2.16/2.88 μg/mL in comparison to 512/1024 μg/mL for pure streptomycin, respectively against E. coli .…”

Section: Gold Nanoparticles and Their Antibacterial Applicationsmentioning

confidence: 99%

“…The AuNPs synthesized using E. coli cells were functionalized with streptomycin and observed to have a significant reduction in MIC/MBC to 2.16/2.88 μg/mL in comparison to 512/1024 μg/mL for pure streptomycin, respectively against E. coli . These AuNPs were also found to be effective against streptomycin‐resistant strains of C. perferingens and C. botulinum ; and showed MIC/minimal bactericidal concentration (MBC) 64/2048, and 128/(not known), respectively . In another report, the AuNPs were synthesized using Bacillus sp.…”

Section: Gold Nanoparticles and Their Antibacterial Applicationsmentioning

confidence: 99%

Advances in the Experimental and Theoretical Understandings of Antibiotic Conjugated Gold Nanoparticles for Antibacterial Applications

2019

View full text Add to dashboard Cite

The worldwide bacterial resistance to a wide range of antibiotics originates a global health concern and calls for the development of new antibacterial agents. Over the recent years, nanomaterials-based agents have been proven to be useful for the effective antibacterial applications. Notably, the gold nanoparticles (AuNPs) draw particular attention due to their biological inertness and easy surface functionalization. It is now established that the antibiotic functionalization on the AuNPs surfaces increases the antibacterial efficacy even towards the antibiotic-resistant bacterial cells. Moreover, the antibacterial efficacy can be further enhanced by photothermal therapy using antibiotic conjugated AuNPs. In this review article, we have reviewed the advances in the development of the synthesis methods of antibiotic conjugated AuNPs and gold nanoclusters, and their antibacterial efficacy. We have also discussed the developments in the theoretical understandings behind the interaction of antibiotic molecules with gold surface and its relation to the antibacterial activity. We believe that few parameters including the selection of antibiotic molecules, the method of its attachment to AuNPs, the purification of antibiotic conjugated AuNPs, and the quantification of conjugated antibiotic are crucial and needs to be properly addressed. Moreover, there are many other future directions discussed, for using antibiotic conjugated AuNPs more effectively for antibacterial therapy.[a] Dr.

show abstract

“…Another approach to combat high-spectrum antibiotic-resistant bacteria involves augmenting the antibacterial action of antibiotics through the use of other agents. Gold nanoparticles (AuNPs), known for their inherent non-cytotoxic nature [15,16], have shown promise in enhancing the bactericidal activity of antibiotics such as carbapenems [17], linezolid [18], and streptomycin [19]. Various synthesis methods can be employed to produce AuNPs [20].…”

Section: Introductionmentioning

confidence: 99%

The Magic Cocktail: Ampicillin and Biosynthesized Gold Nanoparticles Synergism against Staphylococcus aureus

Oliveira,

Soares,

Sá

et al. 2023

Applied Sciences

View full text Add to dashboard Cite

Gold nanoparticles (AuNPs) have garnered attention as a potential alternative to conventional antibiotics due to their innovative antibacterial properties. This study demonstrates the successful production of biosynthetic gold nanoparticles (bAuNPs) using Pseudomonas aeruginosa (P. aeruginosa) as spherical nanostructures at 58 °C for 24 h, under alkaline pH (9.0). The successful synthesis of bAuNPs was confirmed through UV-Vis spectroscopy, exhibiting a characteristic peak within the 500–600 nm wavelength range, and the evaluation of the main functional groups and morphology were stressed by Fourier Transform Infrared Spectroscopy (FT-IR) and Transmission Electron Microscopy (TEM), respectively. Subsequently, the synthesized bAuNPs were combined with low concentrations of ampicillin and evaluated against Methicillin-Susceptible Staphylococcus aureus (MSSA) and Methicillin-Resistant Staphylococcus aureus (MRSA) through the classical serial dilution method. This innovative approach holds the potential to address the escalating issue of antibiotic resistance, providing a viable and sustainable solution.

show abstract

Gold Nanoparticle Biosynthesis by E. coli and Conjugation with Streptomycin and Evaluation of its Antibacterial Effect

Cited by 10 publications

References 0 publications

Preparation of Gold Nanoplates Using Ortho Carbonyl Compounds as Capping Agents for Electrochemical Sensing of Lead Ions

Preparation of Gold Nanoplates Using Ortho Carbonyl Compounds as Capping Agents for Electrochemical Sensing of Lead Ions

Advances in the Experimental and Theoretical Understandings of Antibiotic Conjugated Gold Nanoparticles for Antibacterial Applications

The Magic Cocktail: Ampicillin and Biosynthesized Gold Nanoparticles Synergism against Staphylococcus aureus

Contact Info

Product

Resources

About