Gold Nanoparticle-Coated Magnetic Graphene Oxide as a Dual-Mode Immunochromatographic Biosensor for Enrofloxacin Residue Analysis in Food Samples

Abstract

Enrofloxacin (ENR) is a commonly used veterinary antibiotic and poses a health risk when present as residues in food. This study describes a dual-mode immunochromatographic test strip (DITS) biosensor for the detection of ENR residues in food. Magnetic graphene oxide nanoparticles (MGO-NPs) are twodimensional magnetic nanomaterials with a large specific surface area and fine biocompatibility, which can better provide more adsorption points for biological antibodies. Gold nanoparticles (AuNPs) can stimulate the localized surface plasmon resonance effect under laser irradiation, which will increase the temperature to achieve photothermal conversion. The photothermal conversion efficiency of MGO-NPs can be effectively enhanced by combining AuNPs with MGO-NPs to form MGO@Au nanocomposites