Gold nanoparticle-enabled biological and chemical detection and analysis

Jans, Hilde; Huo, Qun

doi:10.1039/c1cs15280g

Cited by 671 publications

(437 citation statements)

References 151 publications

(166 reference statements)

Supporting

Mentioning

430

Contrasting

Unclassified

Order By: Relevance

“…The questions on organizational performance was adopted from (Huo, 2012), these measures comprised 10 items. The managers and employees were required to specify their level of achievement in relative to the ten measures in their companies.…”

Section: Methodsmentioning

confidence: 99%

The Ripple Effects of Performance Management on Employees’Perceptions and Affective Commitment among Small and Medium Scale Enterprises (SMEs)

Asamany¹,

Sun²

2017

IJBA

View full text Add to dashboard Cite

Management literature acknowledges the important role played by performance management systems (PMS) in business organization, however, a little empirical studies exist in the Ghanaian context.Using a sample data of 180 from managements and staffs of thirty-eight (38) Small and Medium Scale Enterprises (SMEs), the current study presents the effects of performance management systems on employees perception and organizational commitment (affective) among Small and Medium Scale Enterprises (SMEs) located in the Greater Accra region of Ghana.Statistical Package for Social Sciences 20.0 version (SPSS) and Microsoft Word 2010 were employed for the data analysis. From the result, performance management had a positive significant relationship with employees" perceptions and affective organizational commitment.The study further examined the mediating role of both employees" perceptions and affective commitment on performance management towards operational performance, it was revealed that both variables positively mediate the relationship between performance management and organizational performance of the SMEs in Ghana. This indicates that SMEs in Ghana have seen the need for implementing proper performance management systems based on their own capabilities to ensure effectiveness in meeting the organizational objectives.

show abstract

Section: Methodsmentioning

confidence: 99%

The Ripple Effects of Performance Management on Employees’Perceptions and Affective Commitment among Small and Medium Scale Enterprises (SMEs)

Asamany¹,

Sun²

2017

IJBA

View full text Add to dashboard Cite

show abstract

“…1-3 These novel materials, which exhibit unique structures and properties, have been useful in many biosystems as diagnostic probes, nanocarriers and biomarkers. [4][5][6][7] Owing to their small size, it is possible to use nanomaterials to probe, adjust and control biological processes at the cellular and subcellular level. In particular, manufactured nanocarbon materials, including fullerenes, carbon nanotubes, carbon nanohorns and graphene, have been shown to be extremely useful in various biology-related applications such as nanomedicine, drug delivery and biolabeling.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic applications of low-toxicity spherical nanocarbon materials

Wang

et al. 2014

NPG Asia Mater

View full text Add to dashboard Cite

Nanocarbon materials have received considerable attention due to their unique structure and properties, which make them promising candidate materials for use in biomedical applications. In this review, we discuss the therapeutic applications of spherical nanocarbon materials, including fullerene nanoparticles, carbon nanohorn aggregates, nanodiamonds and porous carbon nanospheres, and their toxicology in biological systems. We put special emphasis on the antitumor effects of these multifunctional nanoparticles, which operate via novel mechanisms in a highly efficient manner. The low toxicities of these spherical nanocarbon materials as well as the possible effects of shape on toxicity are discussed.

show abstract

“…Besides, it could be used for tumor ablation by PTT, especially for treating MDR cancers by combining with other therapeutic methods. However, the synthetic method of some gold nanoparticles, such as nanoshells, nanostars, and nanorods, is quite complicated, while some stabilizing agents used for synthesis are toxic to normal cells 109. Moreover, some surface‐modified gold nanoparticles are less stable in saline solutions; thus, more biocompatible molecules, such as PEG, transferrin, and phospholipids, are required for surface modification to improve the stability of gold nanoparticles 110…”

Section: Inorganic Nanocarriers Overcoming Drug Resistance For Cancermentioning

confidence: 99%

Inorganic Nanocarriers Overcoming Multidrug Resistance for Cancer Theranostics

et al. 2016

View full text Add to dashboard Cite

Cancer multidrug resistance (MDR) could lead to therapeutic failure of chemotherapy and radiotherapy, and has become one of the main obstacles to successful cancer treatment. Some advanced drug delivery platforms, such as inorganic nanocarriers, demonstrate a high potential for cancer theranostic to overcome the cancer‐specific limitation of conventional low‐molecular‐weight anticancer agents and imaging probes. Specifically, it could achieve synergetic therapeutic effects, demonstrating stronger killing effects to MDR cancer cells by combining the inorganic nanocarriers with other treatment manners, such as RNA interference and thermal therapy. Moreover, the inorganic nanocarriers could provide imaging functions to help monitor treatment responses, e.g., drug resistance and therapeutic effects, as well as analyze the mechanism of MDR by molecular imaging modalities. In this review, the mechanisms involved in cancer MDR and recent advances of applying inorganic nanocarriers for MDR cancer imaging and therapy are summarized. The inorganic nanocarriers may circumvent cancer MDR for effective therapy and provide a way to track the therapeutic processes for real‐time molecular imaging, demonstrating high performance in studying the interaction of nanocarriers and MDR cancer cells/tissues in laboratory study and further shedding light on elaborate design of nanocarriers that could overcome MDR for clinical translation.

show abstract

Gold nanoparticle-enabled biological and chemical detection and analysis

Cited by 671 publications

References 151 publications

The Ripple Effects of Performance Management on Employees’Perceptions and Affective Commitment among Small and Medium Scale Enterprises (SMEs)

The Ripple Effects of Performance Management on Employees’Perceptions and Affective Commitment among Small and Medium Scale Enterprises (SMEs)

Therapeutic applications of low-toxicity spherical nanocarbon materials

Inorganic Nanocarriers Overcoming Multidrug Resistance for Cancer Theranostics

Contact Info

Product

Resources

About