Gold nanoparticles capped with polysaccharides extracted from pineapple gum: Evaluation of their hemocompatibility and electrochemical sensing properties

Lopes, Luma Clarindo; Lima, Dhésmon; Hacke, Ana Carolina Mendes; Schveigert, Bianca Siqueira; Calaça, Giselle Nathaly; Simas, Fernanda Fogagnoli; Pereira, Romaiana Picada; Iacomini, Marcello; Viana, Adriano Gonçalves; Pessôa, Christiana Andrade

doi:10.1016/j.talanta.2020.121634

Cited by 24 publications

(9 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, the area value (area CPS·eV) of the hydroxyl (-OH) group at 532.7 eV in the O 1s binding energy region decreased in the presence of Cu 2+ (Figure S17a). This can be additional evidence of the Cu 2+ -induced dissociation of polysaccharide networks in the PSNs. , Similarly, after reaction of the PSNs with Cu 2+ , decreases in the peaks of C–O and C–C bonds (286.5, 285.0 eV) were also observed, which is attributed to the degradation of the PSNs (Figure S17b). In the binding energy region of S (Figure c), the peak at 168.68 eV corresponds to the sulfate moieties (−OSO 3 – ) of ι-CG. , Due to spin–orbit coupling, the S 2p signal of the PSNs consists of a 2p 3/2 and 2p 1/2 doublet with ∼1.2 eV division with a 2:1 ratio .…”

Section: Resultsmentioning

confidence: 77%

“…This can be additional evidence of the Cu 2+ -induced dissociation of polysaccharide networks in the PSNs. 52,53 Similarly, after reaction of the PSNs with Cu 2+ , decreases in the peaks of C−O and C−C bonds (286.5, 285.0 eV) 54 were also observed, which is attributed to the degradation of the PSNs (Figure S17b). In the binding energy region of S (Figure 6c), the peak at 168.68 eV corresponds to the sulfate moieties (−OSO 3 − ) of ι-CG.…”

Section: ■ Results and Discussionmentioning

confidence: 86%

See 1 more Smart Citation

Optical Detection of Copper Ions via Structural Dissociation of Plasmonic Sugar Nanoprobes

et al. 2022

View full text Add to dashboard Cite

Heavy metal ions are known to cause environmental pollution and several human diseases because of their inherent toxicity. Among them, Cu 2+ is an essential element for the human body, but its continuous exposure and accumulation may cause adverse effects. Thus, copper ion levels in aquatic environments are strictly regulated by international standards. Herein, we demonstrate a simple optical method for detecting Cu 2+ using plasmonic sugar nanoprobes (PSNs) composed of gold nanoparticles and polysaccharides. Gold precursors were reduced to nanoparticles and spontaneously embedded in the sugar-based polymeric network with the sulfated residues of carrageenan during the polymerization procedure. Owing to the abundant functional residues of PSNs and their affinity toward Cu 2+ , we observed the Cu 2+ -mediated preferential dissociation of the PSNs, resulting in absorbance spectral shifts and scattering shifts of the PSNs. Based on these plasmon band shifts, Cu 2+ below the EPA regulation level of 20 μM can be easily detected by the optimized experimental condition. Additionally, the reaction mechanism between the PSNs and Cu 2+ was elucidated by indepth spectroscopic analyses, which revealed that the increased binding of Cu 2+ to the sulfate groups in the PSNs induces the eventual decomposition of the PSNs.

show abstract

Section: Resultsmentioning

confidence: 77%

Section: ■ Results and Discussionmentioning

confidence: 86%

Optical Detection of Copper Ions via Structural Dissociation of Plasmonic Sugar Nanoprobes

et al. 2022

View full text Add to dashboard Cite

show abstract

“…With occurring cell death, TOB is consequently released into the solution. As shown in Table , all obtained %RSD values were approximately 5% or lower, which is acceptable for the development of new analytical methods, − and presents a good level of precision. Tukey’s multiple comparison tests were performed in order to better evidence the differences existing among the %TOB presented in the results in Table .…”

Section: Resultsmentioning

confidence: 59%

Electrochemical Quantification of Tobramycin Retention in Pseudomonas aeruginosa as Antimicrobial Susceptibility Indicator

et al. 2022

Self Cite

View full text Add to dashboard Cite

The emergence and spread of bacterial resistance to antibiotics has developed into one of the most challenging threats to public health. Antibiotic susceptibility tests (ASTs) for bacterial infections are now essential, because they provide guidance for physicians in the selection of antibiotics, to which bacteria will respond. Most current AST methods require long periods of time, because of bacterial growth and incubation, leading to a prolonged and overuse of broad-spectrum antibiotics. Thus, there is a growing demand for methods and technologies that enable rapid antibiotic susceptibility assessment. Due to advantages related to cost-effectiveness, rapid response time and high sensitivity, electrochemical detection methods are promising analytical tools that can successfully quantify antibiotic uptake and retention in clinically relevant bacterial strains. This study presents the electroanalytical quantification of tobramycin (TOB) retention in susceptible and resistant bacterial strains of Pseudomonas aeruginosa. The electrochemical behavior of TOB was characterized by voltammetry, identifying redox potentials, the current dependence on pH conditions, and the detection limit at unmodified glassy carbon electrodes. The presented methodology was able to distinguish between susceptible and resistant bacterial strains, and is also capable of identifying varying degrees of resistance against TOB. The presented approach detects the immediate interaction of bacteria with an antibiotic, without the need of complex and cost-intense equipment related to genomic testing methods.

show abstract

“…That is, when researchers design electrode materials, EIS is used at each step of the electrode construction process to conrm successful immobilisation of electrode modications. Literature reports that use EIS only in this way have been discounted from this section (there are several examples of this that were ltered from this review from 2021 and 2020 7,[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] ). Instead, this section seeks to present literature reports of EIS when used as the technique of choice for generating a quantitative analytical signal.…”

Section: Applied Electrochemical Impedance Spectroscopymentioning

confidence: 99%

A review of electrochemical impedance spectroscopy for bioanalytical sensors

Randviir

Banks

2022

Anal. Methods

View full text Add to dashboard Cite

show abstract

Gold nanoparticles capped with polysaccharides extracted from pineapple gum: Evaluation of their hemocompatibility and electrochemical sensing properties

Cited by 24 publications

References 74 publications

Optical Detection of Copper Ions via Structural Dissociation of Plasmonic Sugar Nanoprobes

Optical Detection of Copper Ions via Structural Dissociation of Plasmonic Sugar Nanoprobes

Electrochemical Quantification of Tobramycin Retention in Pseudomonas aeruginosa as Antimicrobial Susceptibility Indicator

A review of electrochemical impedance spectroscopy for bioanalytical sensors

Contact Info

Product

Resources

About