Gold nanoparticles protected by fluorinated ligands: Syntheses, properties and applications

Abstract

Abstract:The development of fluorinated gold nanoparticles is presently arising and increasing attention across several fields of nanotechnology. The synthetic approaches evolved over time from the use of almost perfluorinated alkanethiols and perfluorinated arylthiols to amphiphilic fluorinated thiols capable of ensuring solubility in conventional organic solvents and water. The interest in these systems stems from the unique properties of both nanosized and fluorous compounds. In perspective, the development of our understanding of the fluorophilic interactions at the nanoscale will allow to devise novel strategies for self-assembly, molecular recognition and new materials for biomedical applications. In this paper we present, through selected examples, the potential of fluorous ligands in the synthesis of gold nanoparticles and the relevance of mastering the properties of these systems in the development of new materials.

Novel fluorinated ligands for gold nanoparticle labelling with applications in 19F-MRI

“…6 Some research groups have focused their attention on the synthesis of nanoparticles (NPs) decorated with fluorinated ligands to increase the local concentration of fluorine. 10 The group of Pasquato synthesised gold NPs coated with either thiolated PFCs modified with ethylenglycol moieties 11 or perfluorinated ethylenglycol 2 | J. Name., 2012, 00, 1-3 This journal is © The Royal Society of Chemistry 20xx…”

Fluorinated MRI Contrast Agents and Their Versatile Applications in the Biomedical Field

“…Boccalon et al [60] have reported the synthesis of a dual fluorescence/ 19 F MRI probe composed of fluorinated amphiphilic ligands, protecting gold nanoparticles, to which several ligand-dyes 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 Article Body Template can be introduced. In 2015, Pengo et al [61] have reviewed an overall description of different fluorinated gold nanoparticles as well as their properties and possible applications.…”

Structure and Stability of 7-mercapto-4-methylcoumarin SAM on Gold: an Experimental and Computational analysis.

“…Since their first description, 1 thiol self-assembled monolayers (SAM) on gold surfaces and nanoparticles have been widely used in a variety of technological applications, [2][3][4][5][6][7][8][9][10][11][12][13] and studied with a wealth of diffraction, 14-18 spectroscopic 8, [19][20][21][22][23] and other surface science techniques. 24 In addition, thiol SAMs have been modeled theoretically by several ab initio (mainly density functional theory, DFT) [25][26][27][28][29][30][31][32] and molecular mechanics 27,28,[33][34][35][36][37][38] studies.…”