Gold Nanoparticles Sensitized ZnO Nanorods Arrays for Dopamine Electrochemical Sensing

Abstract

One-dimensional nanostructure materials offer opportunities for improving performance of electrochemical sensors. In this work, vertically ZnO nanorods (ZNRs) sensitized with gold nanoparticles (GNPs) were designed and fabricated onto indium tin oxide coated polyethylene terephthalate (ITO/PET) film for dopamine sensing. ZNRs that helpful for electric signal collecting by providing electron transfer pathways were electrodeposited on ITO/PET film firstly. Then GNPs that possess excellent electrocatalytic activity toward target were decorated onto ZNRs via potentiodynamic electrodeposition. These gold nanoparticles sensitized ZnO nanorods arrays (GNPs/ZNRs) combine the advantages of GNPs and ZNRs, thus providing chance to develop electrochemical sensors with ultrahigh sensitivity and excellent selectivity. Several important nervous system diseases (such as Parkinson's disease, schizophrenia, senile dementia, AIDS, et al.) have proved to be associated with dysfunctions of dopamine system. So, the detection of dopamine becomes essential in clinical medical practice and nerve physiology study. When used for dopamine sensing, the fabricated electrochemical sensor shows two linear dynamic ranges (0.01-20 μM and 50-1000 μM) toward dopamine. Moreover, this proposed electrochemical sensor has been successfully applied to the determination of dopamine in human urine with satisfied recoveries (95.3% to 111.3%) and precision (1.1% to 8.4% of RSD).

Electrochemical Determination of Adrenaline Using MXene/Graphite Composite Paste Electrodes

“…Chronoamperogram of the AD with various concentrations in PBS (pH 7.4) with a 30 s time interval at a potential of 1.2 V is shown in Figure b. The current obtained from chronoamperometry was plotted against the concentration of AD (Figure c), and the resultant plot exhibits two linearities, one in the lower concentration range (0.02–10 μm) and other in the higher concentration range (10–100 μm) . From this plot, the lower detection limit of the modified electrode toward AD is calculated as 9.5 nM.…”

“…The current obtained from chronoamperometry was plotted against the concentration of AD (Figure 7c), and the resultant plot exhibits two linearities, one in the lower concentration range (0.02−10 μm) and other in the higher concentration range (10−100 μm). 40 From this plot, the lower detection limit of the modified electrode toward AD is calculated as 9.5 nM. The effect of pH on the voltammetric determination of AD with modified electrode was examined over various pH range ranging from 5.4 to 9.4.…”

A core-shell molybdenum nanoparticles entrapped f-MWCNTs hybrid nanostructured material based non-enzymatic biosensor for electrochemical detection of dopamine neurotransmitter in biological samples

“…To date, electrochemical techniques have been extensively explored for the detection of DA owing to their remarkable properties such as fast detection, facile operation mode, accessibility, cost-effectiveness, simplicity, and eco-friendly 4,20,21 . However, the electrochemical detection of DA in a biological fluid using bare electrode is often unsuccessful due to interfering molecules such as an Ascorbic acid (AA) and Uric acid (UA) coexisting with DA detection because of its similar oxidation potential 22 . As a result, the accuracy of its determination is remarkably low, so it is impossible to avoid their presence in real samples.…”

Optimization of the Perturbation Amplitude for EIS Measurements Using a Total Harmonic Distortion Based Method

“…On the other hand, EIS deals with materials in which ionic conductivity dominates over electronic conductivity [2]. To date, this technique has been applied in a wide range of applications, such as supercapacitors [3][4][5], corrosion [6][7][8][9][10][11], solar cells [12][13][14], electrolysers [15][16][17][18], electrochemical sensors [19][20][21], batteries [22][23][24][25], and fuel cells [26][27][28][29], amongst others. Today, it is considered as one of the fundamental electrochemical techniques [30].…”