Gold nanoparticles/tetraaminophenyl porphyrin functionalized multiwalled carbon nanotubes nanocomposites modified glassy carbon electrode for the simultaneous determination of p-acetaminophen and p-aminophenol

Application of Nanostructured Carbon-Based Electrochemical (Bio)Sensors for Screening of Emerging Pharmaceutical Pollutants in Waters and Aquatic Species: A Review

“…It is important to emphasize the pertinence of this sensor for environmental analysis as its disposable and low-cost characteristics make it suitable for in-situ analysis. Two other acetaminophen sensors were developed, however, with lower performance [ 110 , 111 ]. In the first case, a carbon paste electrode of MWCNT and mineral oil was used for the simultaneous detection of acetaminophen and three other phenolic compounds (hydroquinone, catechol, and 4-nitrophenol) by DPV in the presence of a cationic surfactant in order to promote electron transfer by lowering the detection overpotential and increasing the peak currents.…”

“…Although obtaining a wide linear range, the sensitivity achieved was inferior compared with the two previous described acetaminophen sensors. River water samples were directly analyzed for the drug content by DPV with no traces being found however no traces of the drug were found [ 111 ]. Noteworthy and unusually, a boron-doped diamond (BDD) electrode was also modified simply by depositing Nafion ® -dispersed MWCNT and employed as transducer.…”

“…Conversely, for tetracycline, the CB sensor (GCE/CB-PS [ 137 ]) outperformed compared with graphene (GCE/graphene/L-cysteine [ 74 ]) and MWCNT (GCE/MWCNT-Nafion ® [ 120 ]), which obtained exactly the same LOD value (0.12 μmol L −1 ) whereas for trimethoprim the CB sensor (GCE/CB-CuPh [ 138 ]) presented also higher value of LOD (about 20-times higher) compared with the MWCNT (CPE(MWCNT-SbNPs) [ 124 ]). In turn, LOD of sensors for acetaminophen based on graphene (GCE/graphene-PDDA [ 82 ]), MWCNT [CPE(MWCNT) [ 110 ] and GCE/MWCNT-CONH-TAPP/AuNPs [ 111 ]) and CNF (SPCNFE [ 151 ]) are in line with each other, except for Au/MWCNT-CuNPs [ 109 ] that achieved an approximately 10-fold lower value, while in both CB sensors (GCE/AgNPs-CB/PEDOT:PSS [ 141 ] and SPE/CB(BP) [ 140 ]) values vary widely by 2 orders of magnitude. By analyzing the data, we can conclude therefore that there is not a clear tendency for the impact of the type of carbon nanomaterial in the reached sensitivity.…”

Gold–Carbon Nanocomposites for Environmental Contaminant Sensing

“…Generally, these unique structures possess novel physicochemical properties which develop new types of applications [ 46 , 47 ]. During recent years, numerous gold-based nanocomposites have been established as follows: gold–carbon nanotube nanocomposites [ 48 , 49 , 50 ], polymer–gold nanocomposites [ 51 , 52 , 53 ], graphene–gold nanocomposites [ 54 , 55 , 56 ], biomolecule–gold nanocomposites [ 57 , 58 ], metal oxide–gold nanocomposites [ 59 , 60 ]. Different gold-based nanocomposites have been used in diverse fields such as sensors [ 61 , 62 , 63 ], biosensors [ 64 , 65 , 66 ], optics [ 67 , 68 , 69 ], and medical areas [ 70 , 71 , 72 ].…”

Recent advances in electroanalytical drug detection by porphyrin/phthalocyanine macrocycles: developments and future perspectives

“…12,13 Regarding the selected porphyrins for electroanalytical sensor applications, the differences in their structure are the specific peripheral functional groups, which can provide a strong interaction with the electrodes, either via covalent or electrostatic forces. In this sense, porphyrins containing amino, 14 pyridyl, 15 carboxylate 16 or even acid chloride units 17 are the most used. The presence of metals in the porphyrin cavity also favors electrocatalytic processes, due to the appropriate redox potentials of the metal ions used, for example, porphyrins containing Cu(II), 18 Mn(III) 19 or Fe(III) 20 ions (Fig.…”