Gold nanorods: Synthesis and optical properties

The morpho-functional assessment of plasmonic photothermal therapy effects on transplanted liver tumor

“…is small. 18 On the other hand, Morphologically tumors in the comparison group of rats had a lobed structure; segments were separated by thin layers of connective tissue. Tumor cells had oval-rounded shape with eccentrically located nuclei.…”

“…18 To prevent nanoparticles aggregation in biological tissue and enhance biocompatibility, nanoparticles were functionalized with thiolated polyethyleneglycol (Mw ¼ 5000, Nektar, USA) by previously established method. 23 Geometrical parameters of gold nanorods were determined from analysis of transmission electron microscopy (TEM) images (Libra-120, Carl Zeiss, Germany) by using standard graphic editor.…”

“…The main optical resonance of nanorods is easily adjusted by changing their axial ratio. 18 It causes promising prospects of their use for optical photothermolysis of tumor cells.…”

Study of Tumour and Surrounding Tissue Heating with Near-Infrared Radiation after the Injection of Gold Nanoparticles into the Tissue

“…[11,23]. The GNR geometric parameters determined by means of transmission electron microscopy (Libra-120, Carl Zeiss, Germany) amounted to 41 ± 8 nm (length) and 10 ± 2 nm (diameter).…”

“…Nanoparticles possessing plasmon resonance near 800 nm are effectively applied as sensitizers, which makes it possible to use lasers with the appropriate generation wavelength as sources of radiation [8,9]. It has been shown that gold nanorods (GNRs) are promising agents for photothermal tumour therapy (PTTT) due to their long-term circulation in blood flow [10], colloidal stability, easy spectral tuning of plasmon resonance [6], and efficient light-to-heat energy conversion [11].…”