Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis
Ying Qian,
Shanchuan Ma,
Rong Qiu
et al.
Abstract:Ferroptosis, a form of cell death driven by iron‐dependent lipid peroxidation, is emerging as a promising target in cancer therapy. It is regulated by a network of molecules and pathways that modulate lipid metabolism, iron homeostasis and redox balance, and related processes. However, there are still numerous regulatory molecules intricately involved in ferroptosis that remain to be identified. Here, we indicated that suppression of Golgi protein acyl‐coenzyme A binding domain A containing 3 (ACBD3) increased… Show more
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