2022
DOI: 10.21203/rs.3.rs-1856084/v1
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Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy

Abstract: Background Carbon tetrachloride (CCL4) is highly toxic to animal liver and is a major factor leading to liver injury. Gomphrena globosa L. (GgL) is a comestible plant with anti-inflammation and antioxidation properties. This study was aim to investigate the potential therapeutic effects of GgL on liver injury. Methods and Results A mice model of chronic liver injury was established by intraperitoneal injection of CCl4 (0.4 mL/kg) for 3 weeks, and the mice were treated intraperitoneally with different concentra… Show more

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