The aim of this study was to examine the impact of the obesity status on serum uric acid in health check-up examinees. The study subjects were 1,118 adults, 20 years and over (636 males, 482 females), the health package check-up at the general hospital in Gwang-Ju from January to December, 2011. This study assessed the serum uric acid, blood urea nitrogen, and creatinine levels, as well as the anthropometric variables (SBP, DBP, and BMI). In a model Ⅰ, after adjusting for the variables, such as age, SBP, DBP, TC, TG, HDL-C, and FBG, the mean uric acid level (M±SE) increased with increasing obesity status in males (p<0.001) or females (p=0.036). In model Ⅱ, after adjusting for BUN and creatinine, the mean uric acid (M±SE) .08 mg/dl) (p<0.001). In the females, however, the mean uric acid (M±SE) did not increase with increasing obesity status (Normal weight, 5.03±0.08 mg/dl; overweight, 5.19±0.11 mg/dl; obesity, 5.27±0.09 mg/dl) (p=0.191). In conclusion, these results suggest that an increase in obesity status is associated with an increase in the serum uric acid levels in males, but not in females.