Gonioscopy-assisted Transluminal Trabeculotomy: An Ab Interno Circumferential Trabeculotomy: 24 Months Follow-up

Grover, Davinder S.; Smith, Oliver J.; Fellman, Ronald L.; Godfrey, David G.; Gupta, Aditi; de, Ildamaris Montes; Feuer, William J.

doi:10.1097/ijg.0000000000000956

Cited by 138 publications

(139 citation statements)

References 19 publications

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“…Our combined surgery technique is different from that reported by Grover et al, 18 because cataract extraction with phacoemulsification and intraocular lens implantation was performed first followed by GATT. The author prefers to perform GATT surgery after removing the cataract because it deepens the anterior chamber improving visualization of angle structures and surgical maneuverability.…”

Section: Discussionmentioning

confidence: 73%

“…GATT is a minimal-invasive ab interno procedure with a reported mean IOP reduction from 33% to 65% at 12 months [13][14][15][16][17][18][19] and a success rate (depending on various criteria) ranging from 63% to 89% at 12 and 24 months, respectively. 13,15,17 Our results regarding treatment success (65%) are consistent with the aforementioned reports.…”

Section: Discussionmentioning

confidence: 99%

“…The cumulative proportion of failure in our study (6.3% at 6 and 12 months) is consistent with several reports showing failure rates from 3.1 to 9%. 13,18,19 Higher failure rates (18-40%) are seen in eyes with previous glaucoma filtrating surgery or more advanced glaucoma. 13,20 It has been reported that eyes with more advanced disease (visual field MD worse than −15 dB) 18 had a higher risk of surgical failure, and some authors believe to be due to an atrophy of the collector channels.…”

Section: Discussionmentioning

confidence: 99%

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<p>Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma</p>

Loayza-Gamboa¹,

Martel-Ramirez²,

Inga-Condezo³

et al. 2020

OPTH

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Purpose: To describe the clinical outcomes of combined prolene gonioscopy assisted transluminal trabeculotomy (GATT) with phacoemulsification in patients with open-angle glaucoma. Methods: Retrospective study of patients with cataract and open-angle glaucoma treated with GATT and phacoemulsification with intraocular lens (IOL) implantation. Patients with neovascular glaucoma, corneal decompensation, unstable IOL, and with bleeding disorders were excluded. The cumulative probability of failure was the primary outcome. Secondary outcomes were the complete success rate, the mean change on intraocular pressure (IOP), best-corrected visual acuity (BCVA) and number of glaucoma medications at the last followup. The frequency of complications was also recorded. Results: Thirty two eyes (25 patients) were included. Nineteen (59.3%) were females, with a mean age of 73.4±12.4 (23-87 years) and a mean baseline BCVA of 1.1±0.75 (0.3-3) LogMAR units. The cumulative probability of failure was 3.2% at 1 month and 6.3% at 6 and 12 months. Sixty-eight and 65.5% of eyes achieved complete success at 3 and 6 months, respectively. The reduction of IOP and number of glaucoma medications at 6 months were statistically significant (p<0.0001 and p=0.0002, respectively). There was a statistically significant improvement of BCVA (from 1.1±0.7 to 0.4±0.7) at 6 months (p<0.0001). IOP spikes (18.7%) and transient hyphema (9.3%) were the most common complications. Conclusion: Combined GATT with cataract surgery reduced the IOP and was associated with low failure rates and few ocular complications. This procedure offers the advantage to avoid the need for a bleb, scleral, or conjunctival incision, allowing the possibility for future glaucoma procedures.

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Section: Discussionmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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<p>Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma</p>

Loayza-Gamboa¹,

Martel-Ramirez²,

Inga-Condezo³

et al. 2020

OPTH

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“…Eyes with secondary open angle glaucoma had a greater mean percentage of IOP decrease (49.8%) than eyes with POAG (37.3%). Additionally, eyes with POAG that were already pseudophakic at the time of GATT tended to have a higher cumulative proportion of failure and a higher cumulative proportion for reoperation after the 2 year time point [29].…”

Section: Gonioscopy-assisted Transluminal Trabeculotomymentioning

confidence: 94%

“…Grover et al reported the 2 year results of 198 patients with various open angle glaucoma subtypes who underwent GATT with and without cataract extraction [29]. Eyes with secondary open angle glaucoma had a greater mean percentage of IOP decrease (49.8%) than eyes with POAG (37.3%).…”

Section: Gonioscopy-assisted Transluminal Trabeculotomymentioning

confidence: 99%

An Update on Microinvasive Glaucoma Surgery Concurrent With Cataract Extraction

Tassel

Chen

2019

Curr Ophthalmol Rep

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Purpose of Review In this article, we review the current options for microinvasive glaucoma surgery (MIGS) combined with cataract extraction in the USA and the efficacy of the various approaches. Recent Findings MIGS is a rapidly growing area of research and clinical interest. Available surgeries aim to reduce intraocular pressure by improving aqueous outflow through the trabecular or subconjunctival pathways or by reducing aqueous production. Summary Multiple approaches to MIGS are utilized in clinical practice. On average, these surgeries are safe and modestly effective in reducing intraocular pressure. Future research will demonstrate which surgical approaches are most efficacious, whether and how to combine MIGS, and the role of MIGS in improving patient quality of life.

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Minimally invasive trabecular meshwork surgery for open-angle glaucoma

Vemulapalli

Gandhewar

et al. 2022

Cochrane Database of Systematic Reviews

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Gonioscopy-assisted Transluminal Trabeculotomy: An Ab Interno Circumferential Trabeculotomy: 24 Months Follow-up

Abstract: The 24-month results demonstrate that GATT is relatively safe and effective in treating various forms of open-angle glaucoma. The long-term results for GATT are relatively equivalent to those previously reported for GATT and ab externo trabeculotomy studies.

Cited by 138 publications

References 19 publications

<p>Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma</p>

<p>Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma</p>

An Update on Microinvasive Glaucoma Surgery Concurrent With Cataract Extraction

Minimally invasive trabecular meshwork surgery for open-angle glaucoma

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