Goniothalamin – a potent mosquito larvicide from Bryonopsis laciniosa L.

Abstract

Goniothalamin isolated from the indigenous plant, Bryonopsis laciniosa L., was highly effective against the larvae of the mosquito, Culex quinquefasciatus Say, as a mosquitocide. This is the first report of goniothalamin. The structure of the bioactive compound isolated from the EtOAc (CH 3 COOC 2 H 5 ) fraction was established through spectroscopic methods using 1 H-NMR and 13 C-NMR in CDCl 3 . The mass spectrum was also recorded using VG micromass ZAB mass spectrometer.

Effects of the essential oils of Lippia turbinata and Lippia polystachya (Verbenaceae) on the temporal pattern of locomotion of the mosquito Culex quinquefasciatus (Diptera: Culicidae) larvae

“…Vector control remains a primary element in the current global strategy for the control of vector-borne diseases (Zaim and Jambulingam 2004). The search for natural larvicides and efficient pesticide substances with low environmental toxicity is increasing (Chantraine et al 1998;Kabir et al 2003;Silva et al 2004). Essential oils extracted from aromatic plants are good candidates, since they are, in some cases, highly bioactive, easily available in tropical countries and economically viable (Silva et al 2008;Gleiser and Zygadlo 2008).…”

Larvicidal and Structure–Activity Studies of Natural Phenylpropanoids and Their Semisynthetic Derivatives against the Tobacco Armyworm Spodoptera litura (Fab.) (Lepidoptera: Noctuidae)

“…Some of the compounds under study, i.e., bScheme. Comparative Benefits of Dihydrosafrole (16) over an Isomeric Mixture of Safrole asarone (8), methyleugenol (11), and eugenol (13), showed delayed mortality, which could be attributed to several factors acting separately or together, viz., the uptake of the active moiety of the compound could be time dependent, leading to a progressive increase in the concentration of the compounds tested and their effect on the larval body, or the active moiety of the compound could be converted into more toxic metabolites in the larval integument and alimentary canal, resulting in time-dependent effects [22].…”

Total syntheses of (R)-argentilactone and (R)-goniothalamin via catalytic enantioselective allylation of aldehydes

“…1). 4 Later it was isolated from Cryptocarya moschata, 5 Bryonopsis laciniosa 6 and various species of Goniothalamus. 7 It is a potential cytotoxic compound that has been demonstrated to have antiproliferative activities in a number of transformed cell lines including MCF-7 (breast carcinoma) and HeLa cells (human cervical carcinoma).…”