Goniotomy for Juvenile Open-Angle Glaucoma

Yeung, Helen H; Walton, David S.

doi:10.1097/ijg.0b013e3181a2fa31

Cited by 28 publications

(13 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies have shown that viscocanalostomy, goniotomy and external trabeculotomy can also be performed in eyes with juvenile-onset open angle glaucoma [20,21,22]. However, these studies have small numbers, are mostly retrospective and do not take into account the long-term structural and functional changes associated with IOP control in these patients.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Structural and Functional Outcomes of Therapy in Juvenile-Onset Primary Open-Angle Glaucoma : A Five-Year Follow-Up

Gupta¹,

Ov²,

Rao³

et al. 2011

Ophthalmologica

View full text Add to dashboard Cite

Objective: To evaluate long-term structural and functional changes of the optic nerve head in medically and surgically treated juvenile-onset primary open-angle glaucoma (JOAG). Methods: Forty-two eyes of 42 consecutive primary JOAG patients presenting between January 2000 and January 2003. Results were analysed for long-term intra-ocular pressure (IOP) control, IOP fluctuation, disc characteristics on a Heidelberg Retinal Tomograph II and for visual field changes over a 5-year period. The parameters were compared between medically and surgically treated eyes. Results: The average age of the patients was 26.8 ± 6.1 years. The average baseline IOP was 35.3 ± 14.9 mm Hg. An IOP control <18 mm Hg was achieved in 84% of eyes that underwent filtering surgery (n = 17), compared to 63% on medical therapy alone (n = 25) at the end of 5 years; log rank test p = 0.38. Over 5 years, 4 eyes showed progression (9.5%) of which 3 had been medically treated and 1 had failed surgery (p = 0.45). Conclusion: A tenth of JOAG eyes showed progression over 5 years, and this was more common in those treated medically. Aggressive IOP lowering may thus be needed in eyes with JOAG.

show abstract

Section: Discussionmentioning

confidence: 99%

Long-Term Structural and Functional Outcomes of Therapy in Juvenile-Onset Primary Open-Angle Glaucoma : A Five-Year Follow-Up

Gupta¹,

Ov²,

Rao³

et al. 2011

Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…However, ab externo trabeculectomy is not recommended as a first-line treatment for JOAG despite the potential for greater IOP reduction [2,7]. Rather, angle-based procedures are preferred as they spare the conjunctiva and avoid the potential of life-long bleb-related complications [2,7,8]. As bleb morphology is critical to ocular health, the potential for long-term bleb-related complications should be emphasized when discussing surgical options with these young patients.…”

Section: Discussionmentioning

confidence: 99%

“…Specifically, Arora et al [ 7 ] observed mean reductions of 10 mm Hg in IOP and 0.7 medications 12 months after ab interno trabeculectomy with the trabectome (NeoMedix Corp., Tustin, CA). Moreover, Yeung and Walton [ 2 ] observed a comparative 12.7 mm Hg reduction in IOP after goniotomy. IOP has also been shown to be reduced by 12.5–16 mm Hg following gonioscopy-assisted transluminal trabeculotomy, with reductions in medications ranging from 1.3–1.74 [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Bilateral XEN Gel Stent Implantation in Juvenile-Onset Open-Angle Glaucoma

Klug

Valle

2020

Case Rep Ophthalmol

View full text Add to dashboard Cite

The purpose of the current case is to report the successful management of juvenile-onset open-angle glaucoma with bilateral XEN Gel Stent (Allegran Inc., Irvine, CA) implantation in a patient first diagnosed during pregnancy with co-existing dysautonomia. Treatment with the XEN Gel Stent provided dramatic reductions in intraocular pressure (IOP), and glaucoma medications sustained up to 23 months postoperatively. The success of this case may suggest that this minimally invasive procedure could be an effective treatment option for younger patients who require substantial reductions in IOP and glaucoma medication burden.

show abstract

“…An advantage of goniotomy over many other glaucoma surgical procedures is that it spares the conjunctiva, thus preserving un-operated conjunctiva for future surgical procedures. Although goniotomy is not a typical choice for aphakic glaucoma or open-angle juvenile glaucoma, some authors suggest its use for these diagnoses [ 25 , 26 ]. In addition, it has also been suggested that there may be a role for prophylactic goniotomy in selected aniridia patients without glaucoma [ 27 ].…”

Section: Surgical Optionsmentioning

confidence: 99%