Simulation engines like Gazebo, Unity and Webots are widely adopted in robotics. However, they lack either full simulation control, ROS integration, realistic physics, or photorealism. Recently, synthetic data generation and realistic rendering advanced tasks like target tracking and human pose estimation. However, when focusing on vision applications, there is usually a lack of information like sensor measurements (e.g. IMU, LiDAR, joint state), or time continuity. On the other hand, simulations for most robotics applications are obtained in (semi)static environments, with specific sensor settings and low visual fidelity. In this work, we present a solution to these issues with a fully customizable framework for generating realistic animated dynamic environments (GRADE) for robotics research. The data produced can be post-processed, e.g. to add noise, and easily expanded with new information using the tools that we provide. To demonstrate GRADE, we use it to generate an indoor dynamic environment dataset and then compare different SLAM algorithms on the produced sequences. By doing that, we show how current research over-relies on well-known benchmarks and fails to generalize. Furthermore, our tests with YOLO and Mask R-CNN provide evidence that our data can improve training performance and generalize to real sequences. Finally, we show GRADE's flexibility by using it for indoor active SLAM, with diverse environment sources, and in a multi-robot scenario. In doing that, we employ different control, asset placement, and simulation techniques. The code, results, implementation details, and generated data are provided as open-source. The main project page is https://eliabntt.github.io/grade-rr while the accompanying video can be found at https://youtu.be/cmywCSD-9TU.