2024
DOI: 10.1038/s41522-024-00607-4
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GOS enhances BDNF-mediated mammary gland development in pubertal mice via the gut-brain axis

Yusong Ge,
Yu Cao,
Jialin Zhang
et al.

Abstract: The “gut-brain axis” is involved in many physiological processes. However, its role in regulating mammary gland (MG) development remains unknown. In this study, we established the mice model of bilateral subdiaphragmatic vagotomy (Vago) to clarify the effects of “gut-brain axis” on MG development in pubertal mice. The results showed that Vago reduced the ratio of Lactobacillus and Bifidobacterium , neuronal excitability in the nucleus of solitary tract (NTS), and s… Show more

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