Gossypol Inhibits Protease and Amylase Activity of Spodoptera littoralis1 Larvae2

Meisner, J.; Ishaaya, I.; Ascher, K. R. S.; Zur, M.

doi:10.1093/aesa/71.1.5

Cited by 32 publications

(29 citation statements)

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“…CT and AMY activities decreased with increased dietary CSM. Dietary gossypol inhibits proteinase and AMY activities in Spodoptera littoralis larvae (Meisner et al, 1978) and in H . armigera cotton bollworm larvae (Wang and Qin, 1996;Abdurakhimov et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Effect of dietary cottonseed meal on growth performance, physiological response, and gossypol accumulation in pre-adult grass carp, Ctenopharyngodon idellus

Liu

Yan

Han

et al. 2016

Chin. J. Ocean. Limnol.

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Cottonseed meal (CM) was used at up to 36.95% content in the diet (replacing 60% of dietary fi sh meal protein) without any negative eff ects on growth performance of pre-adult grass carp (initial body weight, 761 g) under outdoor conditions. A culture trial was conducted in net cages installed in a large concrete pond. Seven isonitrogenous and isoenergetic diets containing a gradient of CM concentrations (0, 12.2%, 24.4%, 36.6%, 48.8%, 54.8%, and 61.0%) as replacement for dietary fi sh meal protein (0, 20%, 40%, 60%, 80%, 90%, and 100%) were formulated. Dietary non-resistant starch (from maize) was inverse to dietary CM. Growth performance and feed utilization of fi sh fed the diets containing CM replacing 0-40% fi shmeal protein were not aff ected after the 6-week feeding trial. Accumulation of hepatopancreatic total gossypol in the hepatopancreas was signifi cantly correlated with free gossypol content in the diets (HTG=88.6+1.5×DFG, R 2 =0.89, P <0.05). Intestinal α-amylase and γ-glutamyl transpeptidase activities rose along with increasing dietary CM level. The structure of the mid-intestinal tissues and the ultrastructure of the enterocyte microvilli were normal when dietary CM was <36.6% (60% protein replacement). Increasing dietary CM content increased serum alanine aminotransferase levels but decreased serum alkaline phosphatase, cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, and albumin ( P <0.05).

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Section: Discussionmentioning

confidence: 99%

Effect of dietary cottonseed meal on growth performance, physiological response, and gossypol accumulation in pre-adult grass carp, Ctenopharyngodon idellus

Liu

Yan

Han

et al. 2016

Chin. J. Ocean. Limnol.

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“…The affinity of gossypol to protein is well established and seems to resemble that of tannins (Feeny, 1970). When gossypol acetate is incubated with the enzyme or its casein substrate, prior to enzyme reaction, there is a marked inhibition of the proteolytic activity (Table 4, after Meisner et al, 1978). The interaction of gossypol is rapid, so the inhibitory effect obtained after 5 min preincubation is similar to that after 30 min.…”

Section: Gossypolmentioning

confidence: 90%

“…A decrease of about 40% in larval amylase and protease activities occurs 1 day after feeding on leaves with a high gossypol content. A gradual decrease in larval weight gain and protease activity is observed in larvae fed an artificial diet containing increasing levels of gossypol (Table 3, after Meisner et al, 1978). The affinity of gossypol to protein is well established and seems to resemble that of tannins (Feeny, 1970).…”

Section: Gossypolmentioning

confidence: 92%

“…Freshly collected cotyledons are provided daily, two per larva. The amount of food intake, larval weight, and digestive enzyme activities are determined after different intervals (Meisner et al, 1978). A semisynthetic diet is prepared according to the method of Shorey and Hale (1965) as modified by Kehat and Gordon (1975).…”

Section: A Assays With Gossypolmentioning

confidence: 99%

“…Secondary compounds present in plants such as saponins (Birk, 1969;Cheeke, 1971;Harber, 1972;Bondi et al, 1973;Applebaum and Birk, 1979), tannins (Haslam, 1966(Haslam, , 1974Swain, 1979), proteinous inhibitors of protein-digesting enzymes (Vogel et al, 1968;Liener and Kalade, 1969;Laskowski and Sealock, 1971;Fritz et al, 1974;Birk, 1976;Richardson, 1977;Ryan, 1979), and gossypol (Abou-Donia, 1976) are widely reviewed. These compounds deter insects and other herbivores from feeding and exert their effect, in many cases, directly on the predator digestive enzymes (Birk et al, 1962(Birk et al, , 1963aApplebaum, 1964;Applebaum et al, 1964a;Ishaaya, 1965;Ishaaya and Birk, 1965;Laskowski and Sealock, 1971;Norris et al, 1971;Rozental and Norris, 1973;Ryan, 1973;Singleton and Kratzer, 1973;Rozental et al, 1975;Jones and Mangan, 1977;Meisner et al, 1978;Griffiths and Moseley, 1980).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Nutritional and Allelochemic Insect-Plant Interactions Relating to Digestion and Food Intake: Some Examples

Ishaaya

1986

Springer Series in Experimental Entomology

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Contemplations and speculations on novel approaches in the control of fungal plant diseases

et al. 1983

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Plant disease control can, in principle, be achieved by direct and indirect methods. Novel approaches in direct plant disease control are illustrated by the group of ergosterol biosynthesis inhibitors. Consideration of their stereochemistry leads to speculations on a more rational design of chiral fungicides, with possibly optimised activity against a wider range of fungi. Studies on the mode of action of ergosterol biosynthesis inhibitors, and of the mechanism of resistance to them in fungi, suggest that these phenomena are not causally related. At least in laboratory mutants, resistance seems to be associated with altered membrane function, which may account for reduced fitness, and, in pathogens, for reduced virulence as well. The results of these studies strengthen the conclusion that knowledge of the modes of action and mechanisms of resistance, at the physiological, biochemical and molecular level, should provide a rationale on which to base the design of new systemic fungicides. As a matter of more immediate practical importance, the implications of the use of fungicide‐synergist combinations in plant disease control are briefly discussed. With respect to indirect plant disease control, novel approaches should be directed towards the activation of host resistance. However, prospects seem to be limited for the successful application of alternative chemicals that act on host resistance mechanisms by, for instance, inducing phytoalexin synthesis. Controlled activation of host resistance by localised sensitisation of resistance mechanisms may, however, become a promising new method of plant disease control in the future.

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Gossypol Inhibits Protease and Amylase Activity of Spodoptera littoralis1 Larvae2

Cited by 32 publications

References 0 publications

Effect of dietary cottonseed meal on growth performance, physiological response, and gossypol accumulation in pre-adult grass carp, Ctenopharyngodon idellus

Effect of dietary cottonseed meal on growth performance, physiological response, and gossypol accumulation in pre-adult grass carp, Ctenopharyngodon idellus

Nutritional and Allelochemic Insect-Plant Interactions Relating to Digestion and Food Intake: Some Examples

Contemplations and speculations on novel approaches in the control of fungal plant diseases

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