Gout and pseudogout of the temporomandibular joint

Calcium pyrophosphate dihydrate arthropathy with condylar destruction of the temporomandibular joint

“…Many of these features are evident on plain X-ray films, but they are more conclusive on computed tomography scans and magnetic resonance imaging. Since TMJ involvement is rare, and laboratory and radiographic studies are nonspecific for CPPD, this entity is rarely suspected preoperatively (6). In this case, based on the clinical and radiographic findings, an initial diagnosis of neoplasm and secondary infection of the left TMJ was made.…”

“…Involvement of the TMJ is rare, and the first report of calcium pyrophosphate dihydrate arthropathy of the TMJ was made by Pritzker et al (1). Only 20 cases of this condition affecting the TMJ have been reported (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). In the literature, this disease develops more frequently in women (16 cases, 80%), particularly those aged 50-60 years (average age, 57.4 years).…”

“…Other associated conditions or diseases include osteoarthritis, hypothyroidism, amyloidosis, trauma, and surgical intervention. In the literature, coexistent systemic diseases considered to be closely associated with CPPD of the TMJ, including diabetes mellitus, CPPD in the wrist and knee, generalized arthritis, polymyalgia rheumatica, hypothyroidism, hypertension and hiatal hernia, have been described in 8 patients out of 20 reported cases (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). CPPD deposition disease of the TMJ usually involves the condyle and fibrocartilage (11 out of 20 cases) (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16).…”

Calcium pyrophosphate dihydrate crystal deposition disease of the temporomandibular joint

“…The mechanism for mass formation in CPPD crystal deposition disease also remains unclear. However, the presence of masses in CPPD crystal deposition disease of the TMJ is common (Pritzker et al , 1976; de Vos et al , 1981; Zemplenyi and Calcaterra, 1985; Gross et al , 1987; Kamatani et al , 1987; Mogi et al , 1987; Lambert et al , 1990; Magno et al , 1992; Chuong and Piper, 1995; Ishida et al , 1995; Onodera et al , 1997; Vargas et al , 1997). The case presented here shows only a small region of calcified material in the joint space.…”

“…Therefore it is surprising that the temporomandibular joint (TMJ), a joint in which fibrocartilage predominates, is rarely affected by CPPD crystal deposition disease. CPPD arthropathy of the TMJ has only been described in 23 cases in the literature (Pritzker et al , 1976; de Vos et al , 1981; Good and Upton, 1982; Zemplenyi and Calcaterra, 1985; Gross et al , 1987; Hutton et al , 1987; Kamatani et al , 1987; Mogi et al , 1987; Lambert et al , 1990; Magno et al , 1992; Chuong and Piper, 1995; Dijkgraaf et al , 1995; Ishida et al , 1995; Pynn et al , 1995; Kurihara et al , 1997; Onodera et al , 1997; Vargas et al , 1997; Aoyama et al , 2000; Osano et al , 2003).…”