Governing factors for preparation of silver nanoparticles using droplet-based microfluidic device

Kašpar, Ondřej; Koyuncu, A. H.; Pittermannová, A.; Ulbrich, Pavel; Tokárová, Viola

doi:10.1007/s10544-019-0435-4

Cited by 31 publications

(21 citation statements)

References 40 publications

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“…These non-toxic and biodegradable particles can act as contrast agents in magnetic resonance imaging or fluorescence imaging, drug carriers for small-molecule delivery, transfection vectors for gene therapy, and enhancers for magnetic hyperthermia [27]. Moreover, superparamagnetic iron particles can be employed in the on-demand release of active ingredients by magnetic positioning and exposure to an external stimulus, e.g., radiofrequency, heat, or in combination with responsive polymers for magnetic drug targeting [114].…”

Section: Nanomaterials Synthesis Platformsmentioning

confidence: 99%

Fabrication and Applications of Microfluidic Devices: A Review

Niculescu

Chircov

Bîrcă

et al. 2021

IJMS

383

208

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Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices.

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Section: Nanomaterials Synthesis Platformsmentioning

confidence: 99%

Fabrication and Applications of Microfluidic Devices: A Review

Niculescu

Chircov

Bîrcă

et al. 2021

IJMS

383

208

View full text Add to dashboard Cite

show abstract

“…single-cell handling, screening, and analysis, 4 DNA encapsulation 13 or nanoparticle synthesis and modication. 14,15 In the case where two or more reacting streams form a droplet, efficient and very fast homogenisation have to be achieved. Internal mixing plays a crucial role in the applications where reaction mechanisms are very fast, typically in milliseconds, i.e.…”

Section: Introductionmentioning

confidence: 99%

“…30 For the experimental evaluation of mixing performance, a variety of microscopic techniques with the aid of ow visualisation by pH-sensitive, coloured and uorescent dyes, have been employed. 14,31,32 Two-dimensional projection of a 3D droplet into a plane has been addressed by Fluorescence-Lifetime Imaging (FLIM) providing three-dimensional information about a tracer distribution for both, quasi-steady ows 32 and rapidly owing droplets. 33 However, a high purchasing cost signicantly hinders the widespread application of this technique.…”

Section: Introductionmentioning

confidence: 99%

Influence of channel height on mixing efficiency and synthesis of iron oxide nanoparticles using droplet-based microfluidics

et al. 2020

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“…Microfluidics have also capacity to regulate temperature during flow, rapid mixing within short interval of time, as well as permitting the addition of supplementary reactants downstream for metal nanoparticle synthesis. Summary of few inorganic nanoparticles is presented in Table 1 [33][34][35][36][37][38][39][40][41][42].…”

Section: Inorganic Nanoparticles Synthesismentioning

confidence: 99%

Microfluidic‐based nanoparticle synthesis and their potential applications

et al. 2021

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Microfluidic-based nanoparticle synthesis and their potential applicationsA lot of substantial innovation in advancement of microfluidic field in recent years to produce nanoparticle reveals a number of distinctive characteristics, for instance, compactness, controllability, fineness in process, and stability along with minimal reaction amount. Recently, a prompt development, as well as realization in the production of nanoparticles in microfluidic environment having dimension of micro to nanometers and constituents extending from metals, semiconductors to polymers, has been made. Microfluidics technology integrates fluid mechanics for the production of nanoparticles having exclusive with homogenous sizes, shapes, and morphology, which are utilized in several bioapplications such as biosciences, drug delivery, and healthcare including food engineering. Nanoparticles are usually well-known for having fine and rough morphology because of their small dimensions including exceptional physical, biological, chemical, and optical properties. Though the orthodox procedures need huge instruments, costly autoclaves, use extra power, extraordinary heat loss, as well as take surplus time for synthesis. Additionally, this is fascinating to systematize, assimilate, in addition, to reduce traditional tools onto one platform to produce micro and nanoparticles. The synthesis of nanoparticles by microfluidics permits fast handling besides better efficacy of method utilizing the smallest components for process. Herein, we will focus on synthesis of nanoparticles by means of microfluidic devices intended for different bioapplications.

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Governing factors for preparation of silver nanoparticles using droplet-based microfluidic device

Cited by 31 publications

References 40 publications

Fabrication and Applications of Microfluidic Devices: A Review

Fabrication and Applications of Microfluidic Devices: A Review

Influence of channel height on mixing efficiency and synthesis of iron oxide nanoparticles using droplet-based microfluidics

Microfluidic‐based nanoparticle synthesis and their potential applications

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