“…Given the disruptive effect of stigma on family cohesion in families with parental substance use, with relatives often experiencing to be "invisible" (99), this study emphasizes the need for applying a developmental and interactional perspective on social support to children and parents with SUDs, as stated by Newcomb ((110), p. 54): "Social support can no longer be considered strictly an external force impinging upon the individual; rather, it must be viewed as an evolving developmental and interactive process between an individual and his or her social environment." Although children of parents with SUDs experience need for connectedness and receiving social support from trusted adults (97,111), which has been shown to be protective in this group of children at-risk (112), feelings of shame and self-blame related to the upbringing may hamper help-seeking in children, with implications for long-term mental and physical health (104,113,114). Previous studies showed that also among parents with SUDs, other mental health difficulties often co-occur (115).…”