Bangladesh has experienced the hardest coronavirus disease 2019 (COVID-19) impact on the socioeconomic sector. The underprivileged group, rickshaw pullers, faced extreme situations due to the pandemic. This rapid cross-sectional study was conducted among 190 rickshaw pullers of Dhaka city. Knowledge, attitude, and practice (KAP) survey was carried out to evaluate their view and COVID-19 response level. Descriptive statistics were calculated. Statistical analyses such as Kruskal–Wallis or Mann–Whitney U tests, Spearman’s rank correlation, the linear regression model, Chi-square test, and Fisher’s exact test were performed where appropriate. The majority of them rated the high impact of COVID-19 on their income and mental health. Age, living with family, accommodation type, income, and COVID-19 infection history were found as associating factors with these impacts. A large number of the study population demonstrated low knowledge level (42.63 percent), moderate attitude level (57.37 percent), and moderate practice level (58.95 percent) toward COVID-19 and the vaccination. Positive attitude could reduce their mental health concern due to the pandemic. The study population mostly used their surrounding people as the main source of COVID-19 information. However, digital media have played a crucial role to disseminate authentic information. Ensuring better socioeconomic conditions can help these highly vulnerable people to be effectively prepared and respond against the pandemic.